SINTESIS DAN KARAKTERISASI CARBON DOTS BERBAHAN DASAR ASAM ASKORBAT SEBAGAI KANDIDAT PENANDA BIOLOGIS KANKER

SAYYIDATI ARISTIFANNIY ROHIM, 091615053001 (2019) SINTESIS DAN KARAKTERISASI CARBON DOTS BERBAHAN DASAR ASAM ASKORBAT SEBAGAI KANDIDAT PENANDA BIOLOGIS KANKER. Thesis thesis, Universitas Airlangga.

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Abstract

This study aimed to synthesize and characterize of carbon dots (CDs) originating from ascorbic acid as biomedical applications. This material could be used for a cancer biomarker. The synthesis used microwave radiation as heating source with time variations. The results showed that the best sample had ± 2 nm and the highest fluorescence intensity which was microwave-irradiated for 3.30 minutes. This sample was conjugated with folic acid (FA) which had functional groups that indicated CDs and folic acid. The result of the cytotoxicity test showed non-toxic doses were 0.6 μM CDs; 0.6 and 6 μM CDs – FA. The best dose was used to cell targeting imaging to bladder cancer cell – line. The explanations about characterizations would be discussed on discussion chapter.

Item Type: Thesis (Thesis)
Additional Information: KKC KK TT. 05-19 Roh s
Uncontrolled Keywords: carbon dots (CDs), ascorbic acid, folic acid, microwave, cancer biomarker
Subjects: R Medicine > R Medicine (General) > R856-857 Biomedical engineering. Electronics. Instrumentation
Divisions: 09. Sekolah Pasca Sarjana
Creators:
CreatorsEmail
SAYYIDATI ARISTIFANNIY ROHIM, 091615053001UNSPECIFIED
Contributors:
ContributionNameEmail
ContributorAndi Hamim Zaidan, M.Si, Ph.DUNSPECIFIED
ContributorSri Puji Astuti W., Dr., M.SiUNSPECIFIED
Depositing User: Tatik Poedjijarti
Date Deposited: 26 Apr 2019 08:07
Last Modified: 26 Apr 2019 08:07
URI: http://repository.unair.ac.id/id/eprint/82055
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