Comparison of IPMP, Chlorine Dioxide and Chlorhexidine Gluconat Contained in Mouthwashes for Reducing Exopolysaccharide on Streptococcus Mutans Biofilms

Sri Kunarti and Agus Subiwahjudi and Ratna Dewi and Tamara Yuanita (2017) Comparison of IPMP, Chlorine Dioxide and Chlorhexidine Gluconat Contained in Mouthwashes for Reducing Exopolysaccharide on Streptococcus Mutans Biofilms. In: International Medical Device and Technology Conference 2017, 2017, MALAYSIA.

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Abstract

Background: Streptococcus mutans is the main bacteria forming biofilms associated with dental carious lesions. S. Mutans utilizes dietary carbohydrates to rapidly synthesize exopolysaccharides (EPS) using glucosyltransferase and fructosyltransferase enzyme. Purpose: This research aimed to assess the effects of three active ingredients of mouthwashes on EPS formed on S.mutans biofilms and to determine which ingredient is the most effective in reducing EPS. Method: This research is an experimental laboratory study with post test only control group design using EPS formed on Streptococcus mutans biofilms. EPS then was fluorescently labelled using alexa fluor 647 dextran conjugate stain and analyzed using Confocal Laser Scanning Microscopy and Fluoview ver 1.7a Software. Results: There is a significant difference between those three active ingredients of mouthwashes in reducing EPS and IPMP significantly eliminates EPS. Conclusion. IPMP has the most potential in eleminating EPS formed on Streptococcus mutans biofilms compared to other active ingredients.

Item Type: Conference or Workshop Item (Paper)
Subjects: R Medicine
R Medicine > RK Dentistry
Divisions: 02. Fakultas Kedokteran Gigi > Concervative
Creators:
CreatorsNIM/NIDN
Sri KunartiUNSPECIFIED
Agus SubiwahjudiUNSPECIFIED
Ratna DewiUNSPECIFIED
Tamara YuanitaUNSPECIFIED
Depositing User: Rudy Febiyanto
Date Deposited: 04 Jul 2019 08:09
Last Modified: 04 Jul 2019 08:09
URI: http://repository.unair.ac.id/id/eprint/84504
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