Aktivitas Antimalaria Fraksi Etil Asetat Daun Johar (Cassia siamea Lamk) Terhadap Pertumbuhan Plasmodium Falciparum Strain G2300 (Resisten Klorokuin) In Vitro

Ekasari, Wiwied and ST, Indah and Sri Wahyuni, Tutik and Widyawaruyanti, Aty and Afraz, Afraz (2014) Aktivitas Antimalaria Fraksi Etil Asetat Daun Johar (Cassia siamea Lamk) Terhadap Pertumbuhan Plasmodium Falciparum Strain G2300 (Resisten Klorokuin) In Vitro. Jurnal Penelitian Tanaman Obat Indonesia Planta Husada, 2 (1). pp. 16-19. ISSN 2338-7130

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Abstract

The aimed of this study was to determinate antimalarial activity of ethyl acetate fraction of Johar leaves (Cassia siamea Lamk). In vitro test of the ethyl acetate fraction performed using G2300 strain of Plasmodium falciparum (chloroquine-resistant) which has been synchronized and incubated for 48 hours. The concentration of the test solution of ethyl acetate fraction were used at 100 ug / ml, 10 ug / ml, 1 ug / ml, 0.1 mg / ml, 0.01 ug / ml. The results showed that the ethyl acetate fraction of C. siamea Lamk leaves have antimalarial activity against P. falciparum G 2300 strains chloroquine resistance with IC50 values was 4.46 ug/ml.

Item Type: Article
Uncontrolled Keywords: C. siamea , P. falciparum G2300, antimalaria
Subjects: R Medicine > RS Pharmacy and materia medica
R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
R Medicine > RS Pharmacy and materia medica > RS200-201 Pharmaceutical dosage forms
Divisions: 05. Fakultas Farmasi
Creators:
CreatorsNIM/NIDN
Ekasari, WiwiedUNSPECIFIED
ST, IndahUNSPECIFIED
Sri Wahyuni, TutikUNSPECIFIED
Widyawaruyanti, AtyUNSPECIFIED
Afraz, AfrazUNSPECIFIED
Depositing User: Mr M. Fuad Sofyan
Date Deposited: 06 Jul 2019 06:15
Last Modified: 06 Jul 2019 06:15
URI: http://repository.unair.ac.id/id/eprint/84667
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