Pengaruh Ekstrak Buah Delima Terstandar 40% Ellagic Acid terhadap Profil Darah Tikus Putih Yang Mengalami Nefrotoksisitas akibat Induksi Gentamisin

Lukiswanto, Bambang Sektiari and Yuniarti, Wiwik Misaco (2017) Pengaruh Ekstrak Buah Delima Terstandar 40% Ellagic Acid terhadap Profil Darah Tikus Putih Yang Mengalami Nefrotoksisitas akibat Induksi Gentamisin. Jurnal Sain Veteriner, 35 (2). pp. 208-215. ISSN 0126-0421, ISSN Online 2407-3733

[img] Text (JURNAL)
10. Pengaruh Ekstrak Buah Delima Terstandar ...-min.pdf

Download (8MB)
[img] Text (PEER REVIEW)
Peer Review Bukti C 10.pdf

Download (1MB)
Official URL: https://jurnal.ugm.ac.id/jsv/article/view/34697

Abstract

The purpose of this study was to determine the effect of pomegranate extract of 40% ellagic acid on blood profile of albino rats that had nephrotoxicity after included with Gentamicin. a total of 32 white rats were divided into four treatment groups, each consisting of eight rats. the four treatment groups were healthy rats (P0), Gentamicin induced rats (P1), Gentamicin induced rats and ellagic acid treatment (P2) and Gentamicin induced rats and standardized Pomegranate extract therapy 40% ellagic acid treatment (P3). After seven days of treatment, blood was taken for blood profile tests. The results showed that in the Gentamicin-induced group (P0), a decrease in blood profile allegedly caused by Gentamicin that could cause damage and impaired renal tubular function. Giving ellagic acid and pomegranate extracts of 40% ellagic acid proved to improve the blood profile of Gentamicin induced rats. This is due to inhibition of renal damage and improved renal function due to antioxidant activity possessed by ellagic acid and pomegranate extract of standardized 40% ellagic acid. Keywords : Gentamicin, kidney, nephrotoxity, blood profile

Item Type: Article
Uncontrolled Keywords: Gentamicin, kidney, nephrotoxity, blood profile
Subjects: S Agriculture > SF Animal culture > SF405.5-407 Laboratory animals
S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine
Divisions: 06. Fakultas Kedokteran Hewan > Klinik Veteriner
Creators:
CreatorsNIM/NIDN
Lukiswanto, Bambang SektiariUNSPECIFIED
Yuniarti, Wiwik MisacoUNSPECIFIED
Depositing User: Nn Erna Dwi Indriyani
Date Deposited: 17 Jul 2019 11:07
Last Modified: 17 Jul 2019 11:07
URI: http://repository.unair.ac.id/id/eprint/84746
Sosial Share:

Actions (login required)

View Item View Item