Soegeng Wahluyo, NIDN. 0010115405 and Kun Ismiyatin, NIDN. 0002046001 and Bambang Purwanto, NIDN. 0028088001 and Indri Safitri Mukono, NIDN. 0014065303 (2017) The Influence of Sodium Fluoride on the Growth of Ameloblasts and Kidney Proximal Tubular Cells. Folia Biologica, 63 (1). ISSN 25337602

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Abstract

Abstract. Fluoride has toxic potential particularly for teeth, bones, and kidney. This study was aimed to investigate the NaF exposure effects on the growth of ameloblasts and kidney proximal tubular cells. Adult male healthy rats were used as experiment models,divided into control and NaF-induced groups. The expression of amelogenin, Bcl-2, and caspase-3 were significantly different in the control and NaF-induced group (P < 0.05). There was no correlation among these proteins in the control group but significant correlation in the NaF-induced group (r = 0.694). There was a significant correlation in proximal tubular cells, as seen from the increase of caspase-3 in the NaF-induced group (r = 0.715).

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