PHOSPHOLIPID COMPLEX AS A CARRIER OF KAEMPFERIA GALANGA RHIZOME EXTRACT TO IMPROVE ITS ANALGESIC ACTIVITY

Idha Kusumawati, NIDN. 0004087003 and Helmy Yusuf, NIDN. 0015077901 (2011) PHOSPHOLIPID COMPLEX AS A CARRIER OF KAEMPFERIA GALANGA RHIZOME EXTRACT TO IMPROVE ITS ANALGESIC ACTIVITY. International Journal of Pharmacy and Pharmaceutical Sciences, 3 (1). pp. 44-46. ISSN 0975-1491

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Official URL: https://innovareacademics.in/journal/ijpps/Vol3Sup...

Abstract

Preparation of phospholipid complex of Kaempferia galangarhizome extract using phosphatidylcholine was intended toimprove the bioavailability of its constituents.  Characteristics and analgesic activity of the extract  and its marker compound, ethyl p‐methoxycinnamate (EPMS), were compared to their phospholipid complex (F.Extract and F.EPMS). Characteristics of the free form and their complexes were analysed by DTA and SEM. Their analgesic activity was determined using writhing test. The complex showed a better analgesic activity compared to the free form of both extract and EPMS at an equivalent dosage.

Item Type: Article
Uncontrolled Keywords: Kaempferia galanga, Ethyl‐p­methoxycinnamate, Phospholipid complexes, Analgesic activity
Subjects: R Medicine
R Medicine > RS Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi
Creators:
CreatorsNIM/NIDN
Idha Kusumawati, NIDN. 0004087003UNSPECIFIED
Helmy Yusuf, NIDN. 0015077901UNSPECIFIED
Depositing User: Mr M. Fuad Sofyan
Date Deposited: 19 Aug 2019 02:06
Last Modified: 19 Aug 2019 02:08
URI: http://repository.unair.ac.id/id/eprint/85782
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