Correlation Between DMF-T/def-t and The Secretion of Salivary HBD-1 in Carious and Non-Carious Group of Children

Retno Indrawati, NIDN. 0012115903 and Hendrik Setia Budi, NIDN. 0010067204 and Muhammad Luthfi, NIDN. 0006036704 and Tamima Izzat Nabella, NIM. 021411131074 and Dien Nisa Aulia, NIM. 021411131077 and Tantiana, NIDN. 0006066007 and Seno Pradopo (2019) Correlation Between DMF-T/def-t and The Secretion of Salivary HBD-1 in Carious and Non-Carious Group of Children. Indian Journal of Public Health Research & Development, 10 (5). pp. 550-554. ISSN 0976-0245E

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Abstract

Background: DMF-T/deft (Decay Missing Filled Teeth) is an index for assessing dental and oral health status, in this case, dental caries. Dental caries is a multifactorial disease with factors namely teeth and saliva, microorganisms, dietary, and time that affecting each other. Human Beta Defensins-1 (HBD-1) is an Antimicrobial Peptides (AMPs) that has a role as an adaptive immune system in oral health, is a factor that affects the susceptibility and development of dental caries that exhibits activity in Streptococcus mutans bacteria. Objective: To prove the relationship between DMF-T/deft and the levels of HBD-1 saliva secretion in the carious and non-carious groups of children. Method: This study was an observational analytic with cross-sectional study design, with the division of 3 groups namely; group 1 (DMF-T/deft = 0, caries-free), group 2 (DMF-T/deft = 1-3, low caries), and group 3 (DMF-T/deft > 6, high caries). Result: DMF-T/deft index (1,000) obtained HBD-1 concentration (-0.451). Low DMF-T/deft index has high HBD-1 concentration, whereas high DMF-T/deft index has low HBD-1 concentration. The value of p < (0.05) showed there was a significant correlation between the DMF-T/deft index with salivary HBD-1 concentrations. Conclusion: There was a relationship between DMF-T/deft and the level of HBD-1 saliva secretion in the carious and non-carious groups of children.

Item Type: Article
Uncontrolled Keywords: DMF-T/def-t, Saliva, Streptococcus mutans, Dental Caries, Human Beta Defensins-1
Subjects: R Medicine
R Medicine > RK Dentistry
Divisions: 02. Fakultas Kedokteran Gigi > Oral Biology
Creators:
CreatorsNIM/NIDN
Retno Indrawati, NIDN. 0012115903UNSPECIFIED
Hendrik Setia Budi, NIDN. 0010067204UNSPECIFIED
Muhammad Luthfi, NIDN. 0006036704UNSPECIFIED
Tamima Izzat Nabella, NIM. 021411131074UNSPECIFIED
Dien Nisa Aulia, NIM. 021411131077UNSPECIFIED
Tantiana, NIDN. 0006066007UNSPECIFIED
Seno PradopoUNSPECIFIED
Depositing User: Rudy Febiyanto
Date Deposited: 28 Aug 2019 01:18
Last Modified: 22 Oct 2019 08:22
URI: http://repository.unair.ac.id/id/eprint/85923
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