Ambonese banana stem sap (Musa paradisiaca var. sapientum) effect on PDGF-BB expressions and fibroblast proliferation in socket wound healing

Hendrik Setia Budi, NIDN. 0010067204 and Indah Listiana Kriswandini, NIDN. 0030106303 and Sri Agung Sudjarwo, NIDN. 0004095603 (2016) Ambonese banana stem sap (Musa paradisiaca var. sapientum) effect on PDGF-BB expressions and fibroblast proliferation in socket wound healing. International Journal of ChemTech Research, 9 (12). pp. 558-564. ISSN 0974 – 4290

[img] Text (SIMILARITY)
jurnal 14Ambonese banana stem sap (Musa paradisiaca var. sapientum) effect on PDGF-BB expressions and fibroblast proliferation in socket wound healing.pdf

Download (3MB)
[img] Text (ARTIKEL)
558-564_V9N12CT-1.pdf
Restricted to Registered users only

Download (501kB) | Request a copy
[img] Text (VALIDASI)
pereview 14.pdf

Download (2MB)
Official URL: http://sphinxsai.com

Abstract

TGF-β1 and PDGF-BB are potent chemotaxis, mitogen and diffentiation mesenchym cells active in wound healing. Ambonese banana stem sap has been commonly used historically for gastric bleeding, ulcus pepticum and pharyngitis as empirical agents.The aim of this study is to prove PDGF-BBexpression and fibroblast proliferation effect of ambonese banana stem sap (Musa paradiaca var sapientum) on socket wound healing post tooth extraction. The contains of banana stem sap was performed by thin-layer chromatography (TLC) and ultra-violet visible (UV-vis). We have used the post-test only control-group design with 54 male rats.Incisor and mandible teeth were extracted, and then the socket was treated water extract of ambonese banana stem sap 15, 30 and 60 mg dose in 4% hydroxypropylmethylcellulose (HPMC).The socket were observed at 2, 7 and 14 days on immunohistochemistry (IHC) and histology data. Result of this study that the water extract contains saponnins, flavonoids, tannins, anthraquinon and lectin at screening test. The data showed significant difference of PDGF-BB expressions and fibroblast proliferation at p=0,00 and p=0,00 on days 2 and 7after tooth extraction.The conclusion wasthe water extract of ambonese banana stem sap have potential to accelerate socket wound healing post tooth extraction on PDGF-BB expression and fibroblast proliferation.

Item Type: Article
Subjects: R Medicine
R Medicine > RK Dentistry
Divisions: 02. Fakultas Kedokteran Gigi > Oral Biology
Creators:
CreatorsNIM/NIDN
Hendrik Setia Budi, NIDN. 0010067204UNSPECIFIED
Indah Listiana Kriswandini, NIDN. 0030106303UNSPECIFIED
Sri Agung Sudjarwo, NIDN. 0004095603UNSPECIFIED
Depositing User: Rudy Febiyanto
Date Deposited: 28 Aug 2019 01:57
Last Modified: 28 Aug 2019 01:57
URI: http://repository.unair.ac.id/id/eprint/85979
Sosial Share:

Actions (login required)

View Item View Item