Pengaruh Ekstrak Batang Pisang Ambon (Musa paradisiaca var. sapientum) Terhadap Gambaran Histopatologi Jejunum Tikus (Rattus norvegicus) Inflammatory Bowel Disease

Raditya Dimas Prayoga, 061211131065 and Rochmah Kurnijasanti, NIDN. 0019077004 and Poedji Hastutiek, NIDN. 0003116103 (2016) Pengaruh Ekstrak Batang Pisang Ambon (Musa paradisiaca var. sapientum) Terhadap Gambaran Histopatologi Jejunum Tikus (Rattus norvegicus) Inflammatory Bowel Disease. Journal of Basic Medical Veterinary, 5 (1). pp. 16-21. ISSN 2302-6820

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Abstract

This research aimed to study the effect of Ambon banana hump (Musa paradisiaca var. sapientum) extract to prevent destruction on jejunum, and as well as observe the difference of histopathology of indomethacine induced rat (Rattus norvegicus) in jejunum. This research used about 30 male rats 8 – 12 week, with average weight 150 gram. They were randomly selected and devided into 5 groups. K(-) was given 0,5 ml CMC Na 0,5% for 9 days and 0,5 ml corn oil was given on day 10. K(+) was given 0,5 ml CMC Na 0,5% for 9 days and then was induce by 30 mg/kg BW indomethacine once time on day 10. P1, P2, P3 were given ambon banana hump extract (P1: 20 mg/150 g BW, P2: 40 mg/150 g BW, P3: 80 mg/150 g BW) after that, were induced by 30 mg/kg BW Indomethacine once time on day 10. Each jejunum spesimen was processed and the histopathological changes were observed. Score of submucosal edema and epithelial integrity as qualitative data were analyzed with Kruskal Wallis test continued by Mann-Whitney test. The result were 1) ambon banana hump extract was not significant in reducing jejunum submucosal edema induced by indomethacine, 2) ambon banana hump extract was not significant in reducing jejunum epithelial integrity induced by indomethacine. Keywords : indomethacine, ambon banana hump (Musa paradisiaca var. sapientum), jejunum

Item Type: Article
Uncontrolled Keywords: indomethacine, ambon banana hump (Musa paradisiaca var. sapientum), jejunum
Subjects: S Agriculture > SF Animal culture > SF405.5-407 Laboratory animals
S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine
Divisions: 06. Fakultas Kedokteran Hewan > Ilmu Kedokteran Hewan Dasar
Creators:
CreatorsNIM/NIDN
Raditya Dimas Prayoga, 061211131065UNSPECIFIED
Rochmah Kurnijasanti, NIDN. 0019077004santisam99@yahoo.co.id
Poedji Hastutiek, NIDN. 0003116103UNSPECIFIED
Depositing User: Nn Erna Dwi Indriyani
Date Deposited: 04 Sep 2019 08:12
Last Modified: 04 Sep 2019 08:12
URI: http://repository.unair.ac.id/id/eprint/86149
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