Effect of electrolyzed reduced water on Wistar rats with chronic periodontitis on malondialdehyde levels

Rini Devijanti Ridwan, NIDN. 0016126404 and Wisnu Setyari Juliastuti, NIDN. 0010075702 and R. Darmawan Setijanto, NIDN. 0005106109 (2017) Effect of electrolyzed reduced water on Wistar rats with chronic periodontitis on malondialdehyde levels. Majalah Kedokteran Gigi (dental Journal), 50 (1). pp. 10-13. ISSN 1978-3728

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Abstract

Background: Periodontal disease is a progressive destructive change that causes loss of bone and periodontal ligaments around the teeth that can eventually lead to its loss. The main bacteria in chronic periodontitis is Porphyromonas gingivalis. Aggregatibacter actinomycetemcomitans, a pathogen associated with aggressive periodontitis, initiates a proinflammatory response that causes tissue destruction of periodontal, alveolar bone resorption and subsequent tooth loss. Electrolyzed reduced water (ERW) is an alkaline water, ERW not only has a high pH and low oxidation reduction potential (ORP), but also contains several magnesium ions. Magnesium ions proven effective for the prevention of various diseases. Purpose: To analyze the level of malondialdehyde (MDA) in Wistar rats with cases of chronic and aggressive periodontitis that consumed ERW. Method: Wistar rats were divided into four groups, each group with 10 rats. The first and second group were Wistar rat with chronic periodontitis and consume drinking water and ERW. The third and fourth group were Wistar rat with aggressive periodontitis and consume drinking water and ERW. This experiment is done by calculating the levels of MDA. The calculation of the levels of MDA is done with spectrophotometric assay for MDA. Result: The results of this experiment show that the level of MDA in serum in group that consume ERW had decreased significantly different with thegroup that consume drinking water with the statistical test. Conclusion: It can be concluded that ERW can decrease the MDA level in Wistar rat with chronic and aggressive periodontitis case.

Item Type: Article
Uncontrolled Keywords: chronic periodontitis; aggressive periodontitis; electrolyzed reduced water; malondialdehyde level; Wistar rat
Subjects: R Medicine
R Medicine > RK Dentistry
Divisions: 02. Fakultas Kedokteran Gigi > Dental Public Health
Creators:
CreatorsNIM/NIDN
Rini Devijanti Ridwan, NIDN. 0016126404UNSPECIFIED
Wisnu Setyari Juliastuti, NIDN. 0010075702UNSPECIFIED
R. Darmawan Setijanto, NIDN. 0005106109UNSPECIFIED
Depositing User: Rudy Febiyanto
Date Deposited: 17 Sep 2019 08:25
Last Modified: 17 Sep 2019 08:25
URI: http://repository.unair.ac.id/id/eprint/86761
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