DETERMINATION OF RETENTION TIME OF MEDROXY PROGESTERONE ACETATE UNDER STORAGE TIME USING HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY

ASRI KARUNIAWATI, 061511133093 (2019) DETERMINATION OF RETENTION TIME OF MEDROXY PROGESTERONE ACETATE UNDER STORAGE TIME USING HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

The aim of this research was to determine the retention time of chromatogram Medroxy Progesterone Acetate (MPA) dissolved in a solvent named Mobile Phase Eluent (MPE) after being stored for six, eight and 12 hours using High Performance Liquid Chromatography (HPLC). This research used posttest-only control group design with three treatments and six replications. The three treatments were 6, 8 and 12 hours storage time. Data obtained were analyzed by One-Way Anova. The result showed retention time of MPA at 6 hours (T1) and 8 hours (T2) storage time were stable but were not for 12 hours (T3) storage time appeared irrelevant peaks indicates the substance where was starting to break down. Based on those result, it could be concluded that Medroxy Progesterone Acetate in Mobile Phase Eluent began to show instability at 12 hours of storage time.

Item Type: Thesis (Skripsi)
Additional Information: KKC KK KH 221/ 19 Kar d
Uncontrolled Keywords: Medroxy Progesterone Acetate, stability, retention time, High Performance Liquid Chromatography (HPLC)
Subjects: S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine > Including veterinary genetics, ethology, anatomy, physiology, embryology, pathology
Divisions: 06. Fakultas Kedokteran Hewan
Creators:
CreatorsNIM/NIDN
ASRI KARUNIAWATI, 061511133093UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorSuzanita Utama, NIDN : 0002106104UNSPECIFIED
ContributorMochamad Lazuardi, NIDN : 0018125804UNSPECIFIED
Depositing User: Mrs. Djuwarnik Djuwey
Date Deposited: 21 Sep 2019 06:58
Last Modified: 21 Sep 2019 06:58
URI: http://repository.unair.ac.id/id/eprint/87230
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