Hospital and Community Based Surveilance of Zika and Dengue Viruses in Indonesia

Nasronudin Suharto and Muhammad Amin, NIM011328226303 and Diah Puspita Rini, NIDN. 0001057915 and Achmad Chusnu Romdhoni, NIDN. 0002097604 and Purwaningsih Zulfayandi Pawanis and Muhammad Syamsul Hidayat (2017) Hospital and Community Based Surveilance of Zika and Dengue Viruses in Indonesia. African Journal of Infectious Diseases (AJID), 12 (01). pp. 20-27. ISSN 2006-0165

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Abstract

Background: Zika virus remained silent for few decades after its first recognition in 1947. Recently, Zika drew global attention due to the outbreak in Pacific island and Latin Americas. The concern was escalating given the shared vector of Zika and dengue with possible deleterious complications. Surabaya as one of the largest cities in Indonesia with high mobility of people is endemic to dengue. This study was aimed to detect Zika infection during dengue outbreaks in Surabaya. Materials and Methods: This was a surveillance study involving patients visiting 4 public hospitals and 8 primary health care centres (PHCs). Patients were recruited if they were suspected to have dengue infection based on WHO guidelines (1997). The recruitment was based on the attendance of the patients at the healthcare facilities until the maximum quota was fulfilled. Dengue serological diagnostic confirmation was based on non-structural protein 1 (NS1) and/or immunoglobulin M (IgM) detection. Zika virus infection was examined using real time polymerase chain reaction (RT-PCR) test. Results: Between February and April 2016, 100 patients consented to participate in this study - 54 females and 46 males. Furthermore, 55 patients were recruited from PHCs and the other 45 patients were from hospitals. Median age was (median (IQR)) 28.6 (14.6) years (range15 to 65 years). Of 100 patients examined, there was no Zika infection detected, but 11 patients were identified to have positive dengue infection with varying clinical and laboratory presentations. Conclusion: Serosurveillance of Zika and dengue infection in Surabaya City found no evidence of Zika infection among those presented to healthcare facilities.

Item Type: Article
Uncontrolled Keywords: Zika,dengue,Surabaya,surveillance,RT-PCR
Subjects: R Medicine > R Medicine (General) > R5-130.5 General works
R Medicine > RF Otorhinolaryngology
Divisions: 01. Fakultas Kedokteran > Ilmu Penyakit THT
Creators:
CreatorsNIM/NIDN
Nasronudin SuhartoUNSPECIFIED
Muhammad Amin, NIM011328226303UNSPECIFIED
Diah Puspita Rini, NIDN. 0001057915UNSPECIFIED
Achmad Chusnu Romdhoni, NIDN. 0002097604romdhoni-a-c@fk.unair.ac.id
Purwaningsih Zulfayandi PawanisUNSPECIFIED
Muhammad Syamsul HidayatUNSPECIFIED
Depositing User: hanif kurniawan
Date Deposited: 30 Sep 2019 08:19
Last Modified: 30 Sep 2019 08:19
URI: http://repository.unair.ac.id/id/eprint/87468
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