Structure Modifications of Pinostrobin from Boesenbergia pandurata Roxb. Schlecht Extract

Andy Suryadi A. M. and Rr. Retno Widyowati, NIDN. 0005017701 and Tri Widiandani, NIDN. 0004128001 and Siswandono, NIDN. 0002105207 (2018) Structure Modifications of Pinostrobin from Boesenbergia pandurata Roxb. Schlecht Extract. In: Bromo Conference, Symposium on Natural Products & Biodiversity, 11-12 July 2018, Surabaya, Indonesia. (Unpublished)

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Abstract

Background: Boesenbergia pandurate Roxb. Schlecht. (Zingiberaceae) is one of the ginger plants that has been identified to contain pinostrobin. It determined as an anti-inflammatory and analgesic activities through inhibition of COX2 enzymes. Objective: The objective of this research was to obtain a pinostrobin derivative of acylation reactions between pinostrobin and acyl chloride derivatives. Methods: The structure modifications of pinostrobin were obtained by Schotten-Baumann method through nucleophilic substitution reactions between pinostrobin and acyl chloride derivatives. Results: The investigation of structure modifications of pinostrobin from this plant has demonstrated the present of pinostrobin acetate (1) and pinostrobin butyrate (2) based on the spectrometric analysis such NMR. Conclusion: Pinostrobin acetate and pinostrobin butyrate which are derivatives of pinostrobin can be synthesized using the Schotten-Baumann method.

Item Type: Conference or Workshop Item (Poster)
Uncontrolled Keywords: Structure modification, Boesenbergia pandurata, pinostrobin, Schotten-Baumann.
Subjects: R Medicine
R Medicine > RS Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi
Creators:
CreatorsEmail
Andy Suryadi A. M.UNSPECIFIED
Rr. Retno Widyowati, NIDN. 0005017701UNSPECIFIED
Tri Widiandani, NIDN. 0004128001UNSPECIFIED
Siswandono, NIDN. 0002105207UNSPECIFIED
Depositing User: Mr M. Fuad Sofyan
Date Deposited: 21 Oct 2019 02:00
Last Modified: 21 Oct 2019 02:00
URI: http://repository.unair.ac.id/id/eprint/87696
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