EFEK PEMBERIAN EKSTRAK ETHANOL DAUN KELOR (Moringa oleifera) TERHADAP GAMBARAN HISTOPATOLOGI HEPAR MENCIT JANTAN YANG DIINDUKSI PARASETAMOL

NIDIA KUSUMAWATI AISYAH, 061311133207 (2019) EFEK PEMBERIAN EKSTRAK ETHANOL DAUN KELOR (Moringa oleifera) TERHADAP GAMBARAN HISTOPATOLOGI HEPAR MENCIT JANTAN YANG DIINDUKSI PARASETAMOL. Skripsi thesis, UNIVERSITAS AIRLANGGA.

[img] Text (Abstrak)
KKC KK KH 246 - 19 Ais e-Abstrak.pdf

Download (22kB)
[img] Text (Daftar isi)
KKC KK KH 246 - 19 Ais e-Daftar isi.pdf

Download (30kB)
[img] Text (Daftar pustaka)
KKC KK KH 246 - 19 Ais e-Daftar pustaka.pdf

Download (26kB)
[img] Text (Fulteks)
KKC KK KH 246 - 19 Ais e.pdf
Restricted to Registered users only until 19 October 2022.

Download (2MB) | Request a copy
Official URL: http://lib.unair.ac.id

Abstract

This research aims was to observe liver histopathological features of mice toward the effect of Moringa oleifera leaves extract to reduce the damage of paracetamol administration. This research used 30 male mice aged 2-3 months with an average body weight of 20-30 grams and using completely randomized design (CRD) method with 5 repetitions for each groups. The negative control group was given 0.5% CMC Na and distilled water, the positive control was given 0.5% CMC Na and paracetamol, while treatments group one, two, and three were given Moringa leaf extract at a dose of 200 mg / kg, 400 mg / kg, 800 mg/kg respectively, then administered paracetamol. At the end of the research, mice are euthanized then liver collection was carried out. The liver collected was made into preparations using H.E staining to observe its histopathological features. According to the results of statistical analysis, there were significant differences (p <0.05) to the histopathological features of the liver in male mice induced by paracetamol between treatment groups. From the results obtained, it can be inferred that the right dose of Moringa oleifera leaves ethanol extract to reduce liver damage due to administration of paracetamol in male mice are 400 mg/ kgBW.

Item Type: Thesis (Skripsi)
Additional Information: KKC KK KH 246/ 19 Ais e
Uncontrolled Keywords: Moringa oleifera, Paracetamol, Liver, Musmusculus.
Subjects: S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine > Including veterinary genetics, ethology, anatomy, physiology, embryology, pathology
Divisions: 06. Fakultas Kedokteran Hewan
Creators:
CreatorsNIM/NIDN
NIDIA KUSUMAWATI AISYAH, 061311133207UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorSetya Budhy, NIDN : 0012077202UNSPECIFIED
ContributorArimbi, NIDN : 0029085603UNSPECIFIED
Depositing User: Mrs. Djuwarnik Djuwey
Date Deposited: 19 Oct 2019 07:09
Last Modified: 19 Oct 2019 07:09
URI: http://repository.unair.ac.id/id/eprint/89467
Sosial Share:

Actions (login required)

View Item View Item