SUGIHALAM GUNAWAN, 0508100187 (2012) POLA PENGGUNAAN INSULIN PADA DM GESTASIONAL ( Studi di Instalasi Rawat Inap SMF Obstetri Ginekologi RSUD Dr. Soetomo Surabaya ). Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

Gestational Diabetes Mellitus (GDM) is a complication in pregnancy and associated with increasing number of morbidity and mortality, so that the management of an appropriate therapy is needed. The objective of this study was to describe the insulin profile and to identify drug related problem in the management of GDM. The study was retrospectively designed by descriptive analysis. It was performed in GDM patients during period of January, 1st 2008 to December, 31st 2011. This study had been reviewed from Ethical Board Dr.Soetomo Teaching Hospital Surabaya, Indonesia. The type of insulin used in this study were rapid-acting insulin Aspart (48%), short-acting Regular Human Insulin (48%), intermediette acting NPH (36%), mixed insulin (Aspart+Neutral Protamined Aspart)(16%) and long-acting Detemir (16%), a patient might receive more than one type and route of insulin administration. The dose was given depending on the blood glucose level and clinical condition of the patient, but generally the rapid regulation of insulin was given by the formula (n- 1)x4 units/h, n was the first number of blood glucose levels. Prandial and basal insulin therapy were usually started with small dosage. The drug related problems were hypoglycemia (16%) and hypokalemia (16%). Administration of insulin along with other therapies might also caused actual interactions, which needed more attention

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