Theresia Indah Budhy S. and Bambang Sumaryono and Ketut Suardita and Amelia Putri Rizkita (2017) BMP-2 Expression of Post Tooth Extraction that Catfish Oil Application. The Veterinary Medicine International Conference 2017, 2017. pp. 69-76.
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BMP-2 Expression of Post Tooth Extraction that Catfish Oil Application.pdf Download (2MB) |
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Validasi dan kelaikan Etik (BMP).pdf Download (1MB) |
Abstract
Background: Catfish (Clarias batrachus) oil contain the highest amount of omega- 3-PUFA among other freshwater fish. The omega-3-PUFA in fish oil produced eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). It is known that EPA and DHA in essentials fatty acid (EFA) could improve BMP-2 expression. Bone morphogenetic protein-2 (BMP-2) is bone stimulator which capable of inducing differentiation of mesenchymal cells into osteoblast, stimulating bone formation in wound healing process of dental extraction. Purpose: To prove the increasing expression of BMP-2 after catfish (Clarias batrachus) oil application. Methods: We have used the post test only design in this research. There have been 21 Rattus novergicus as research samples, and those were divided into 3 groups, group KK as control, group KP1 was given catfish (Clarias batrachus) oil in 5% concentration, and group KP2 was given catfish (Clarias batrachus) oil in 10% concentration. Catfish(Clarias batrachus) oil were applied into the socket of dental extraction. Rat was decapulated 7 days after fish oil application and the jaw in the treated regions and control group were cut for immunohistochemistry examination to observe BMP-2 expression. Data was analyzed using one-way ANOVA test. Result: There is significant difference increased of BMP-2 expression between control and treatment group. In samples given with 10% concentration of catfish oil had the most significant increase of BMP-2 expression. Conclusion: Catfish (Clarias batrachus) oil in 10% concentrationcould increase the expression of BMP-2 post dental extraction.
| Item Type: | Article | ||||||||||
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| Uncontrolled Keywords: | Catfish oil, BMP-2, dental extraction. | ||||||||||
| Subjects: | R Medicine R Medicine > RK Dentistry |
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| Divisions: | 02. Fakultas Kedokteran Gigi > Patologi & Maxifacial | ||||||||||
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| Depositing User: | Rudy Febiyanto | ||||||||||
| Date Deposited: | 03 Dec 2019 08:57 | ||||||||||
| Last Modified: | 23 Mar 2020 03:35 | ||||||||||
| URI: | http://repository.unair.ac.id/id/eprint/91650 | ||||||||||
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