PENGARUH KONSENTRASI KITOSAN TERHADAP PENETRASI ASAM p-METOKSISINAMAT (APMS) DALAM SISTEM NANOEMULSI

KHOZINATUS SA’ADAH, 051111129 (2016) PENGARUH KONSENTRASI KITOSAN TERHADAP PENETRASI ASAM p-METOKSISINAMAT (APMS) DALAM SISTEM NANOEMULSI. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Official URL: http://lib.unair.ac.id

Abstract

The aim of this study is to know the effect of chitosan addition with various concentration on penetration p-methoxycinnamic acid from nanoemulsion system. chitosan is used as thickening agent which act as nanoemulsion droplets stabilizer. Concentration that used for nanoemulsions were without chitosan (Formula I), chitosan 0,05% (Formula II), chitosan 0,15% (Formula III) and chitosan 0,3% (Formula IV). Nanoemulsion system was prepared for transdermal delivery system. In vitro penetration study of nanoemulsion system of p-methoxycinnamic acid through Wistar rat skin was determined using Franz Diffusion Cell. Several parameters, such as flux and membrane permeability were determined. However, according to the result of statistical analysis there was no significant difference on flux and membrane permeability of each formula among others.

Item Type: Thesis (Skripsi)
Additional Information: KKB KK-2 FF.F.26/15 Sa'a p
Uncontrolled Keywords: CHITOSAN; NANOEMULSION
Subjects: K Law > K Law (General) > K1-7720 Law in general. Comparative and uniform law. Jurisprudence > K(520)-5582 Comparative law. International uniform law > K3625-3649 Food. Drugs. Cosmetics
Q Science > QD Chemistry > QD1-999 Chemistry
Divisions: 05. Fakultas Farmasi > Farmastika
Creators:
CreatorsNIM
KHOZINATUS SA’ADAH, 051111129UNSPECIFIED
Contributors:
ContributionNameNIDN / NIDK
Thesis advisorTristiana Erawati M, Dr., Apt., M.SiUNSPECIFIED
Thesis advisorEsti Hendradi, Dra., Hj., Apt., M.Si., Ph.DUNSPECIFIED
Depositing User: Nn Dhani Karolyn Putri
Date Deposited: 19 Feb 2016 12:00
Last Modified: 29 Sep 2016 14:28
URI: http://repository.unair.ac.id/id/eprint/9278
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