UJI AKTIVITAS ANTIKANKER EKSTRAK ETANOL BIJI SRIKAYA (Annona squamosa L.) TERHADAP BEBERAPA SEL KANKER MANUSIA SECARA IN VITRO

I GEDE ISWARA PRANIDHANA PUTRA, 050911206 (2015) UJI AKTIVITAS ANTIKANKER EKSTRAK ETANOL BIJI SRIKAYA (Annona squamosa L.) TERHADAP BEBERAPA SEL KANKER MANUSIA SECARA IN VITRO. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

This aimed study to determine the cytotoxic effect of ethanolic extract of Annona squamosa L. seed against T47D, HeLa, WiDr, and Raji cancer cells. Annona squamosa L. contains annonaceous acetogenin, which known has cytotoxic activity. Cytotoxic test is performed by MTT assay. The parameters obtained from the cytotoxic test was IC50 values. IC50. The results showed that the seeds of Annona squamosa L. have cytotoxic activity with IC50 values were 30.152 ± 2,124 μg/ml ; 33.289 ± 3,001 μg/ml ; 19.862 ± 2,645 ; and 8.008 ± 3,871 μg/ml for T47D cell, WiDr cell, HeLa cell, and Raji cell respectively.

Item Type: Thesis (Skripsi)
Additional Information: KKB KK-2 FF.FT.12/15 Put u
Uncontrolled Keywords: Anticancer, Annona squamosa L., in vitro, MTT method, T47D cell, WiDr cell, HeLa cell, Raji, cell.
Subjects: Q Science > QD Chemistry > QD415-436 Biochemistry
R Medicine > RC Internal medicine > RC0254 Neoplasms. Tumors. Oncology (including Cancer)
Divisions: 05. Fakultas Farmasi > Farmakognosi Fitokimia
Creators:
CreatorsEmail
I GEDE ISWARA PRANIDHANA PUTRA, 050911206UNSPECIFIED
Contributors:
ContributionNameEmail
ContributorHerra Studiawan, Drs., M.S., AptUNSPECIFIED
ContributorLusianan Arifianti, S.Farm., M.Farm., AptUNSPECIFIED
Depositing User: Nn Dhani Karolyn Putri
Date Deposited: 22 Feb 2016 12:00
Last Modified: 21 Sep 2016 02:44
URI: http://repository.unair.ac.id/id/eprint/9292
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