Herlina Novita Hasyim and Abdul Rohim Tualeka and Noeroel Widajati (2017) The Relationship Between Benzene Vapor's Exposure and Immunoglobulin a Among Shoes Worker in the Village of Tambak OSO Wilangun Surabaya. Indian Journal of Public Health Research & Development, 8 (4). pp. 145-150. ISSN 0976-0245

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Abstract

Glue is one of the most important ingredient in the making of shoes, that it contains an organic solvent which is benzene. Benzene solvent in glues known by 1-2%. Benzene is known asa carcinogen category A1,confirmed human carcinogen, meaning that benzene has been ascertained and proven carcinogen in humans. Chronic exposure to benzene affects on cellular and humoral immunity. Benzene evaporates into the air very quickly allowing to be inhaled by workers. The purpose of this study are(1) to measure the levels of benzene vapor in the work environment, (2) to determine the concentration of A Immunoglobulin among workers and (3) to determine the relationship between benzene vapor exposure and workers' IgA concentration. The method used to measure the levels of benzene vapor in the workplace was gas chromatography method using GC / FID (Flame Ionization Detector) and to determine the concentration of A Immunoglobulin, venous blood sampling was done and then analyzed by Immunoturbidimetric Assay. Benzene vapor's levels of shoes workers in workplacewas varied, from 0.0129 ppm to 2.3330 ppm which was 0.5116 ppm in average and IgA concentration experienced a value of 0.86 mg/ml to 3.80 mg/ml. Pearson product moment test was conducted on worker characteristics (age, year of service), Spearman's rank test on nutritional status and contingency coefficient C test for gender and smoking habits with IgA concentration of workers obtained all the variables had a value of p> 0.05.The result showed that the IgA concentrations among workers which were 8 workers noted as under normal (<2 mg/ml) and 8 workers experienced a normal IgA concentration (2-3 mg/ml) while 4 others were above normal (> 3 mg/ml) with ppm benzene levels 0.0129 - 2.3330 ppm and average levels of benzene in the air amounted to 0.5116 ppm>TVL (0.5 ppm). In conclusion, twelve workers witnessed an abnormal IgA concentration (decrease / increase of the normal value).

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