Inhibition of Apoptosis in Retinal of Newborn Mice Due to Congenital Toxoplasmosis

Lucia Tri Suwanti and Mufasirin and Hani Plumeriastuti (2017) Inhibition of Apoptosis in Retinal of Newborn Mice Due to Congenital Toxoplasmosis. Proceeding "The Veterinary Medicine International Conference (VMIC)". pp. 77-83. ISSN 2413-0877

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Abstract

Toxoplasma gondii infection in pregnant women cause defects in the newborn, such as hydrocephalus and eye damaged, even blindness. Histologically damage due to congenital infection of T. gondii need to be examined. Twenty pregnant mice were divided into two groups which are the treatment group and the control group. Each mouse in treatment group was infected with 10 takizoit by intraperitoneal. Each of the newborn were sacrified, their head were taken and their eye tissue were fixed in 10% of buffered formalin and the histological sample were made in HE and TUNEL staining. The result showed that the retina of the eye of the newborn from infected mice damage. The damages include: hemorrhage, infected retinal cells, eye growth inhibition and decreased of apoptosis index of the retina cells. Keywords: Apoptosis in retinal, Newborn, Congenital Toxoplasmosis, Ocular Toxoplasmosis

Item Type: Article
Uncontrolled Keywords: Apoptosis in retinal, Newborn, Congenital Toxoplasmosis, Ocular Toxoplasmosis
Subjects: S Agriculture > SF Animal culture > SF405.5-407 Laboratory animals
S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine > SF811-909 Veterinary medicine of special organs, regions, and systems
Divisions: 06. Fakultas Kedokteran Hewan > Parasitologi Veteriner
Creators:
CreatorsNIM
Lucia Tri SuwantiNIDN0028086208
MufasirinNIDN0011076705
Hani PlumeriastutiNIDN0008085905
Depositing User: Nn Erna Dwi Indriyani
Date Deposited: 15 Apr 2020 05:24
Last Modified: 07 Jan 2021 02:27
URI: http://repository.unair.ac.id/id/eprint/95143
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