PERBANDINGAN STABILITAS ASAM O-(4-METILBENZOIL)SALISILAT DENGAN ASAM O-ASETILSALILSILAT PADA REAKSI HIDROLISIS DALAM pH 11

GLORIA TAUFANI UNGU, 050210170 E (2011) PERBANDINGAN STABILITAS ASAM O-(4-METILBENZOIL)SALISILAT DENGAN ASAM O-ASETILSALILSILAT PADA REAKSI HIDROLISIS DALAM pH 11. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

O-(4-methylbenzoyl) salicylic acid has great potency to be developed furthermore, because it has an analgesic activity that similar with acetyl salicylic acid. This reseach was conducted to compare the stability between O-(4-methylbenzoyl)salicylic acid and acetylsalicylic acid against hydrolysis reaction. The stability was determined by observing the degradation of these compounds in buffer solution pH 11 heated at constant temperature 800 C. The reactan concentration was determined by measuring salicylic acid produced periodically in observed time 180 minutes. The quantitative analysis was doneby spectrophotometry UV method. It was concluded that in condition pH 11,O-(4-methylbenzoyl)salicylic acid was more stable than acetylsalicylic acid .

Item Type: Thesis (Skripsi)
Additional Information: KKB KK FF 248 11 Ung p
Uncontrolled Keywords: SALICYLIC ACID
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi > Kimia Farmasi
Creators:
CreatorsNIM
GLORIA TAUFANI UNGU, 050210170 EUNSPECIFIED
Contributors:
ContributionNameNIDN / NIDK
Thesis advisorSiswandono, Prof. Dr., Apt.,MSUNSPECIFIED
Thesis advisorNuzul WahyuninG Diyah, Dra. ,Apt.,MSiUNSPECIFIED
Depositing User: Dwi Marina
Date Deposited: 26 Jan 2012 12:00
Last Modified: 13 Jul 2016 05:42
URI: http://repository.unair.ac.id/id/eprint/9536
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