Kaempferia Galanga L. Inhibiting Effect On Vascular Endothelial Growth Factor (VEGF) and Cyclooxygenase-2 (Cox-2) Expression on Endothelium of Chorioallantoic Membrane

Iwan Sahrial Hamid and Juni Ekowati and Muhammad Thohawi Elziyad Purnama (2019) Kaempferia Galanga L. Inhibiting Effect On Vascular Endothelial Growth Factor (VEGF) and Cyclooxygenase-2 (Cox-2) Expression on Endothelium of Chorioallantoic Membrane. Indian Veterinary Journal, 96 (9). pp. 80-82. ISSN 0019 - 6479

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Abstract

This study was aimed to examine the extract of Kaempferia galanga L. to inhibit the expression of VEGF and Cox-2 on the chorioallantoic membrane of embryonated chicken eggs (ECE). This study used 24 ECE which were divided into six groups: (C+) inoculated with solvent, (C-, T1, T2, T3 and T4) inoculated with bFGF 60 ng then (T1, T2, T3 and T4) treated with the extract doses of 30, 60, 90 and celecoxib 60 mg, respectively. Expression of VEGF and Cox-2 was observed by the immunohistochemical method. It was concluded that the extract of Kaempferia galanga L. can inhibit the expression of VEGF and Cox-2 on the chorioallantoic membrane.

Item Type: Article
Uncontrolled Keywords: Kaempferia galanga L, VEGF, Cox-2, celecoxib
Subjects: R Medicine
R Medicine > RS Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi
Creators:
CreatorsNIM
Iwan Sahrial HamidNIDN0013076801
Juni EkowatiNIDN0006026703
Muhammad Thohawi Elziyad PurnamaUNSPECIFIED
Depositing User: Mr M. Fuad Sofyan
Date Deposited: 29 Jun 2020 02:58
Last Modified: 29 Jun 2020 02:58
URI: http://repository.unair.ac.id/id/eprint/95740
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