Fluconazole Resistant Oral Candidiasis on HIV Patient - What Other Drug can We Choose? A Case Report

Dwi Murtiastutik and Cita Rosita Prakoeswa and Indah Setyawati Tantular (2020) Fluconazole Resistant Oral Candidiasis on HIV Patient - What Other Drug can We Choose? A Case Report. Journal of Pure and Applied Microbiology, 14 (1). pp. 31-36. ISSN 0973-7510

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Abstract

The majority of HIV / AIDS patients have common secondary infections including of oral candidiasis. Fluconazole can be used to treat oral resistance in candidiasis. Management that can reduce risk can be minimized. However, some evidences suggest that the use of fluconazole is not effective for oral candidiasis. A 34-year-old male patient went to Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, with main complaint of discomfort and pain in the tongue. The physical examination showed a white pseudomembrane on the tongue and palate, which could be removed but left reddish and painful marks. The examination from tongue and palate swab found a colony of white Candida albicans and showed resistant to fluconazole, intermediate to ketoconazole, and sensitive to nystatin. The patient received nystatin oral suspension for three times a day as much as 5 ml (500,000 units). The pseudomembrane disappeared on day 10. The medication continued for fourteen days. No sign of recurrent found in two weeks after the treatment. The administration of nystatin can be used as an effective medication for oral candidiasis.

Item Type: Article
Uncontrolled Keywords: Oral candidiasis, HIV/AIDS patient, fluconazole
Subjects: R Medicine > R Medicine (General)
R Medicine > RB Pathology
Divisions: 01. Fakultas Kedokteran > Ilmu Penyakit Kulit
Creators:
CreatorsNIM
Dwi MurtiastutikNIDN8860010016
Cita Rosita PrakoeswaNIDN8865610016
Indah Setyawati TantularNIDN0029116103
Depositing User: hanif kurniawan
Date Deposited: 30 Jun 2020 05:06
Last Modified: 30 Jun 2020 05:06
URI: http://repository.unair.ac.id/id/eprint/95848
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