New Vesicovaginal Fistula Formation in a Rabbit Model

Eighty Mardiyan Kurniawati and Tri HS Hadi and Nur AR Widiatmoko and Widjiati and Fedik Abdul Rantam and Budi Santoso and Budi I Santoso and Hari Paraton and Gatut Hardianto and Azami Denas Azinar and Boedi Setiawan (2019) New Vesicovaginal Fistula Formation in a Rabbit Model. Majalah Obstetri & Ginekologi, 27 (3). pp. 114-118. ISSN 0854-0381

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Objective: To create an animal model of vesicovaginal fistula as a modality to develop therapy. Material and Methods: This study was an preliminary experimental study to create new fistula vesicovaginal formation in a rabbit model. Six female New Zealand white rabbits of Stem Cell Research and Development Center of Universitas Airlangga were used in this study and were divided into 3 groups in which there were 2 rabbits in each group. Vesicovaginal fistula formation was performed through laparotomy surgery. After the abdomen is opened, the Nasogastric tube is inserted vaginally into the anterior vaginal wall. The incision is made on the anterior vaginal wall and the posterior wall of the bladder. The Nasogastric tube that comes out of the vagina is inserted into the bladder incision to maintain the formation of vesicovaginal fistula. Both mucosal walls are sutured and tested to determine if there is any leak. Evaluation the model of vesicovaginal fistula was carried out 3 weeks postoperatively according the group. Result: Four out of six rabbits have formed vesicovaginal fistulas, which are from groups two and three. There are no complications during the treatment period until termination Conclusion: Rabbits have the potential to become experimental animals for the vesicovaginal fistula model. The best time to release a nasogastric tube to maintain a fistula is 2 weeks.

Item Type: Article
Uncontrolled Keywords: vesicovaginal fistula, animal model
Subjects: R Medicine > R Medicine (General)
R Medicine > RG Gynecology and obstetrics
Divisions: 01. Fakultas Kedokteran > Ilmu Kebidanan dan Kandungan
Eighty Mardiyan KurniawatiNIDN0014087703
Fedik Abdul RantamNIDN0010035907
Budi SantosoNIDN0017026307
Gatut HardiantoUNSPECIFIED
Azami Denas AzinarUNSPECIFIED
Boedi SetiawanNIDN0016037103
Depositing User: hanif kurniawan
Date Deposited: 13 Jul 2020 04:34
Last Modified: 13 Jul 2020 04:34
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