PREPARASI NANOPARTIKEL KITOSAN DENGAN PENAMBAHAN GLUKOSA SEBAGAI KRIOPROTEKTAN (Dibuat dengan Metode Gelasi Ionik � Pengeringan Beku)

YULIANA DWI ANGGRAINI, 050911141 (2013) PREPARASI NANOPARTIKEL KITOSAN DENGAN PENAMBAHAN GLUKOSA SEBAGAI KRIOPROTEKTAN (Dibuat dengan Metode Gelasi Ionik � Pengeringan Beku). Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Official URL: http://lib.unair.ac.id

Abstract

The aim of this research is to investigate the effect of centrifugation, freezing process, and glucose as cryoprotectant on chitosan nanoparticles formation. Nanoparticles was prepared by ionic gelation and freeze dried. Nanoparticles obtained from ionic gelation was separated by centrifugation. The effect of speed and time for centrifugation, freezing temperature were also studied. After thawing, particles that had been processed with centrifuge speed 4000 rpm for 5 minutes and freezed at -30oC for 1 hour indicated spherical shape. Otherwise, SEM image of dried nanoparticles showed that agregation formed after drying for 24 hours.

Item Type: Thesis (Skripsi)
Additional Information: KKB KK-2 FF F 55/13 Win 64/13 Ang p
Uncontrolled Keywords: FREEZE DRYING
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: 05. Fakultas Farmasi > Farmastika
Creators:
CreatorsNIM/NIDN
YULIANA DWI ANGGRAINI, 050911141UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorRetno Sari, Dra. , M. Sc, AptUNSPECIFIED
Depositing User: Dwi Marina
Date Deposited: 07 Jan 2014 12:00
Last Modified: 27 Jul 2016 04:55
URI: http://repository.unair.ac.id/id/eprint/9628
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