PUTRI NARULLITA HIDAYANTI, 050911294 (2013) PREPARASI NANOPARTIKEL KITOSAN DENGAN PENAMBAHAN MALTODEXTRIN SEBAGAI KRIOPROTEKTAN( Dibuat dengan Metode Gelasi Ionik - Pengeringan Beku). Skripsi thesis, UNIVERSITAS AIRLANGGA.
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Abstract
The aim of this research is to determine the effect of centrifugation, freezing step with maltodextrin as cryoprotectant on chitosan nanoparticles formation. Nanoparticles was prepared by ionic gelation and dried by freeze drying. Nanoparticles which had made with ionic gelation was separated by centrifugation. The effect of speed and time for centrifugation, freezing temperature were also studied. The result showed that chitosan nanoparticles had spherical shape after centrifuge at 4000 rpm for 5 minutes and freeze dried at -30°C for 1 hour. Otherwise, SEM image of dried nanoparticles showed that agregation formed after drying for 24 hours.
| Item Type: | Thesis (Skripsi) | ||||||
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| Additional Information: | KKB KK-2 FF F 73/13 Put p | ||||||
| Uncontrolled Keywords: | FREEZE DRYING | ||||||
| Subjects: | R Medicine > RS Pharmacy and materia medica | ||||||
| Divisions: | 05. Fakultas Farmasi > Farmastika | ||||||
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| Depositing User: | Dwi Marina | ||||||
| Date Deposited: | 07 Jan 2014 12:00 | ||||||
| Last Modified: | 27 Jul 2016 08:02 | ||||||
| URI: | http://repository.unair.ac.id/id/eprint/9636 | ||||||
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