PERBANDINGAN STABILITAS ASAM O-(2-KLOROBENZOIL)SALISILAT DAN ASAM O-ASETILSALISILAT PADA pH 11 DAN SUHU 80oC

JOSE JICO HUTAPEA, 050513416 (2013) PERBANDINGAN STABILITAS ASAM O-(2-KLOROBENZOIL)SALISILAT DAN ASAM O-ASETILSALISILAT PADA pH 11 DAN SUHU 80oC. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

This research was done to compare the stability of o-(2-chlorobenzoyl)salicylic acid and o-acetylsalicylic acid had great potency to be developed furthermore, because it has an analgesic activity that similar with o-acetylsalicylic acid. The stability was determined by studying the degradation of these compounds by comparing their physicochemical parameters, which were reaction rate constant (k), half-life period (t½) and shelf life (t90). The degradation of these compounds was done at various time in condition pH 11 at 80˚C. The quantitative analysis was done by spectrophotometry UV method. It was obtain that in condition pH 11. o-(2-chlorobenzoyl)salicylic acid more stable than o-acetylsalicylic acid.

Item Type: Thesis (Skripsi)
Additional Information: KKB KK-2 FF.KF 29/13 Hut p
Uncontrolled Keywords: STABILITAS ASAM
Subjects: Q Science > Q Science (General) > Q179.9-180 Research
Divisions: 05. Fakultas Farmasi
Creators:
CreatorsNIM/NIDN
JOSE JICO HUTAPEA, 050513416UNSPECIFIED
Contributors:
ContributionNameNIDN/NIDK/NUP
ContributorProf. Dr.Siswandono, Apt., MS, Prof. Dr., Apt., MSUNSPECIFIED
Depositing User: shiefti dyah alyusi
Date Deposited: 07 Jan 2014 12:00
Last Modified: 10 Aug 2016 04:31
URI: http://repository.unair.ac.id/id/eprint/9721
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