Protection of Dayak Onion Tuber Extract (Eleutherine palmifolia) Against Kidney Histopathological Appearence of Albino Male Rat Strain Wistar Which was Induced by Alloxan

Dwi Gayatri Nurcahyawati and Hani Plumeriastuti and Lilik Maslachah (2017) Protection of Dayak Onion Tuber Extract (Eleutherine palmifolia) Against Kidney Histopathological Appearence of Albino Male Rat Strain Wistar Which was Induced by Alloxan. The Veterinary Medicine International Conference (VMIC). pp. 702-711. ISSN 2413-0877

[img] Text (Proceeding)
Bukti C 26 Protection of Dayak Onion Tuber ....pdf

Download (1MB)
[img] Text (Peer Review)
Peer review C 26 Protection of Dayak Onion Tuber ....pdf

Download (1MB)
[img] Text (Turn It In)
Bukti C 26 Protection of Dayak Onion Tuber ....pdf

Download (1MB)
Official URL: https://knepublishing.com/index.php/KnE-Life/artic...

Abstract

The purpose of this study was to know the effect of Dayak onion tuber extract (Eleutherine palmifolia) given by per oral in lowering levels of histophatology damage kidney of albino male rat (Rattus norvegicus) strain Wistar which was induced by alloxan. Animals which were used in this research were 24 white male rats (Rattus norvegicus) strain Wistar, and then divided into 6 groups. The negative control group K (-) were given with aquabidest and CMC-Na 1% during the therapy period, the positive control group K (+) were given with alloxan 110 mg / kgbw, the group of drug control K (O) were given with alloxan and oral therapy with metformin 9 mg / 200g bw / day, the treatment group 1 (P1) were given with alloxan and per oral therapy with extract of Dayak onion tuber 100 mg / kgbw, the treatment group 2 (P2) were given with alloxan and per oral therapy with extract of Dayak onion tuber 200 mg / kgbw and the treatment group 3 (P3) were given with alloxan and per oral therapy with extract of Dayak onion tuber 400 mg / kgbw. The therapy was given for 14 days, then the animals were sacrificed with ketamine and then its kidney was taken for examination of hisphatology in kidney. Observations based on their depiction of renal histopathology tubular degeneration and necrosis, glomerular necrosis, intestitial infiltration and glomerular sclerosis. Data obtained from the scoring of histopathological appearence albino rat kidneys were analyzed by test Kruskal-Wallis and if there is a real difference followed by Mann-Whitney test using SPSS 20.0 for windows. The results showed that the extract of Dayak onion tuber 400 mg/ kgbw can reduce the degree of kidney damage in albino male rat exposed to alloxan significantly. Keywords: Eleutherine palmifolia, alloxan, kidney, histhopathology.

Item Type: Article
Uncontrolled Keywords: Eleutherine palmifolia, alloxan, kidney, histhopathology
Subjects: S Agriculture > SF Animal culture > SF405.5-407 Laboratory animals
S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine > SF811-909 Veterinary medicine of special organs, regions, and systems
Divisions: 06. Fakultas Kedokteran Hewan > Ilmu Kedokteran Hewan Dasar
Creators:
CreatorsNIM
Dwi Gayatri NurcahyawatiNIM061311133279
Hani PlumeriastutiNIDN0008085905
Lilik MaslachahNIDN0006116105
Depositing User: Nn Erna Dwi Indriyani
Date Deposited: 09 Sep 2020 02:43
Last Modified: 09 Sep 2020 02:43
URI: http://repository.unair.ac.id/id/eprint/98488
Sosial Share:

Actions (login required)

View Item View Item