The Comparison of Neutropenia and Peripheral Neuropathy Condition as an Impact of 3-hours and 24-hour Paclitaxel Infusion of Paclitaxel-Carboplatin Chemotherapy on Ovarian Cancer Patients

Primandono Perbowo and Brahmana Aksandar and Sunjoto and Ratna Soebadi and Achmad Bashori (2019) The Comparison of Neutropenia and Peripheral Neuropathy Condition as an Impact of 3-hours and 24-hour Paclitaxel Infusion of Paclitaxel-Carboplatin Chemotherapy on Ovarian Cancer Patients. Pain Medicine Journal, 4 (2). pp. 41-52. ISSN 2414-3812

[img] Text (Artikel)
The Comparison.pdf

Download (310kB)
[img] Text (Peer Review)
The Comparison of Neutropenia.pdf

Download (3MB)
[img] Text (Similarity)
The Comparison of Neutropenia and Peripheral Neuropathy Condition as an Impact of 3-hours and 24-hour Paclitaxel Infusion of Paclitaxel-Carboplatin Chemotherapy on Ovarian Cancer Patients.pdf

Download (3MB)
Official URL: https://painmedicine.org.ua/index.php/pnmdcn/artic...

Abstract

This study is aimed to compare the difference of neutropenia with peripheral neuropathy condition, after administration of 3 hours and 24 hours Paclitaxel infusion in adjuvant therapy with Paclitaxel­Carboplatin toward patient with ovarian carcinoma. The method that used was experimental research with samples randomized after consecutively recruited based on inclusive criteria. Before and every after chemotherapy, NCS was performed and differential count laboratories’ test and then analysed with T­test and Chi­square test. The result showed that from three times administration of 3 hours Paclitaxel­Carboplatin infusion group, the neutropenia condition after first up to third chemotherapy was 20 %, 30 %, 30 %, and the peripheral neuropathy condition was 30 %, 60 %, 50 % respectively. Meanwhile, in 24 hours Paclitaxel­Carboplatin infusion group, the incident of neutropenia after first up to third chemotherapy was 40 %, 50 %, 40 %, and the incident of peripheral neuropathy was 20 %, 20 %, 20 % respectively. The statistic result was p > 0.05. Hence, there was no significant difference in neutropenia and peripheral neuropathy incident on two study group.

Item Type: Article
Uncontrolled Keywords: Neutropenia, Peripheral Neuropathy, Paclitaxel, Carboplatin, Ovarian Carcinoma, Neuro Conduction Study
Subjects: R Medicine > R Medicine (General)
R Medicine > RG Gynecology and obstetrics
R Medicine > RG Gynecology and obstetrics > RG1-991 Gynecology and obstetrics
Divisions: 01. Fakultas Kedokteran > Ilmu Kebidanan dan Kandungan
Creators:
CreatorsNIM
Primandono PerbowoNIDN8833800016
Brahmana AksandarNIDN0014057304
SunjotoNIDN0020114801
Ratna SoebadiUNSPECIFIED
Achmad BashoriUNSPECIFIED
Depositing User: hanif kurniawan
Date Deposited: 09 Sep 2020 01:49
Last Modified: 09 Sep 2020 01:49
URI: http://repository.unair.ac.id/id/eprint/98646
Sosial Share:

Actions (login required)

View Item View Item