Fifty Percent Of Food Restriction During Gestation Reduced The Dendritic Density Of Cerebrum And Cerebellum Of Rattus Norvegicus’ Newborn

Anwar Fauzi and Widjiati and Hermanto Tri Joewono (2018) Fifty Percent Of Food Restriction During Gestation Reduced The Dendritic Density Of Cerebrum And Cerebellum Of Rattus Norvegicus’ Newborn. Majala Obstetri dan Ginekologi, 26 (3). pp. 112-117. ISSN 08540381

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Official URL: https://e-journal.unair.ac.id/MOG/article/view/107...

Abstract

Objectives: To analyze the influence of 50 percent food restriction during pregnancy to the dendritic density of cerebellum and cerebellum of newborn Rattus norvegicus. Materials and Methods: Laboratory experimental study with single blind randomized post-test only control group design using animal model; pregnant Rattus norvegicus as treatment models. Subjects were divided into two groups: control group and treatment group which was exposed to 50% food restriction (FR 50%). At day 21, both group sacrificed and the cerebrum and cerebelum of the offsprings were prepared and stained with silver impregnation. We used parametric independent t-test in analyzing dendritic density. Results: In the cerebrum there was a significant difference in dendritic density between control (4.98+2.17) and treatment (2.69+0.76) groups with p=0.001 (p<0.05). In the cerebellum there was ALSO a significant difference in dendritic density between control (7.37+2.23) and treatment groups (3.01+0.64) with p=0.000 (p<0.05). Conclusions: The dendritic density of cerebrum and cerebellum of newborn Rattus norvegicusexposed to 50 percent of food restriction during pregnancy were lower than control.

Item Type: Article
Uncontrolled Keywords: 50 percent of food restriction, pregnancy, dendrite density, Rattus norvegicus newborn cerebrum and cerebellum
Subjects: R Medicine > R Medicine (General)
R Medicine > RG Gynecology and obstetrics
Divisions: 01. Fakultas Kedokteran > Ilmu Kebidanan dan Kandungan
Creators:
CreatorsNIM
Anwar FauziUNSPECIFIED
WidjiatiNIDN0015046204
Hermanto Tri JoewonoNIDN8817900016
Depositing User: hanif kurniawan
Date Deposited: 27 Sep 2020 13:15
Last Modified: 27 Sep 2020 13:15
URI: http://repository.unair.ac.id/id/eprint/99252
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