Aspirin Dosis Rendah Efektif Menurunkan Resistensi Arteri Uterina yang Abnormal pada Ibu Hamil Usia Kehamilan 16–24 Minggu Low Dose

Rachmi and Agus Sulistyono (2016) Aspirin Dosis Rendah Efektif Menurunkan Resistensi Arteri Uterina yang Abnormal pada Ibu Hamil Usia Kehamilan 16–24 Minggu Low Dose. Majalah Obstetri & Ginekologi, 24 (1). pp. 25-30. ISSN 0854-0381

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Official URL: https://e-journal.unair.ac.id/MOG/article/view/795...

Abstract

Objectives: To measure the thickness of elastin fibres on vaginal wall of patients with POP anterior and then analyse the correlation of this measurement with the degree of POP anterior. Materials and Methods: This research is an observational analytic study. Data collection was conducted with a cross sectional approach on 28 blocks paraffin of vaginal wall taken from POP anterior patients of whom went through an operation in Dr. Soetomo Hospital of Surabaya. Data was divided into four groups: degree 0/I , II, III and IV respectively (n = 7). Immunohistochemical staining was performed with antibodies elastin. Afterward, the thickness of the elastin fibres was measured by utilizing a microscope with a Leica Application Suite (LAS) software. Results: We found significant differences in the mean of thickness of elastin fibres in each group of patients with degrees of anterior POP 0/I , II , III and IV respectively 0,81 + 0,14 µm; 1,63 + 0,19 µm; 2,47 + 0,26µm and 3,19 + 0,36 µm (p < 0,0001 ). Based on Pearson correlation test, the results shows a correlation coefficient r = 0.965 (p < 0,0001). Conclusion: The thickness of elastin fibre on vaginal wall increased as the degree of POP anterior arise. Increased in the thickness of elastin fibers on the vaginal walls was the result from extracellular matriks remodelling on vaginal wall of anterior POP patient.

Item Type: Article
Uncontrolled Keywords: Pelvic organ prolapse, elastin, vaginal wall
Subjects: R Medicine > R Medicine (General)
R Medicine > RG Gynecology and obstetrics
Divisions: 01. Fakultas Kedokteran > Ilmu Kebidanan dan Kandungan
Creators:
CreatorsNIM
RachmiUNSPECIFIED
Agus SulistyonoNIDN8810800016
Depositing User: hanif kurniawan
Date Deposited: 12 Oct 2020 03:16
Last Modified: 12 Oct 2020 03:16
URI: http://repository.unair.ac.id/id/eprint/99888
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