Juniastuti and Bogi P. Wibowo and I. D. N. Wibawa and Takako Utsumi and Syifa Mustika and Mochammad Amin and Rury M. Wahyuni and Hendra Kurniawan and Agus Hendrayana and Poernomo Boedi Setiawan and Laura N. Yamani and Soetjipto and Yoshihiko Yano and Hak Hotta and Yoshitake Hayashi and Maria Inge Lusida (2014) Interleukin-28B Polymorphisms and Response of Chronic Hepatitis C Patients from Indonesia to Pegylated Interferon/Ribavirin Treatment. Journal of Clinical Microbiology, 52 (6). pp. 2193-2195. ISSN 1098660X

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Abstract

This study demonstrated that Indonesian patients with chronic hepatitis C (mostly ethnic Java people) mostly were infected with hepatitis C virus (HCV) genotype 1; however, they carried mainly the major genotypes of interleukin 28B (IL-28B) single nucleotide polymorphisms (SNPs) (rs12979860 CC, rs11881222 TT, rs8103142 AA, and rs8099917 TT), and they mostly achieved sustained virological responses to pegylated interferon/ribavirin treatment.

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