Rismita Pritanti (2019) Perbedaan Nilai LED Penderita Demam Berdarah Dengan Hemokonsentrasi Dan Tidak Hemokonsentrasi. Tugas Akhir D3 thesis, UNIVERSITAS AIRLANGGA.

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Abstract

DHF is an infectious disease that often causes epidemics and causes death in many people, this disease is caused by dengue virus and transmitted by the aedes aegypti mosquito. The main cause of dengue fever is the dengue virus, which is a virus from the family Flaviviridae. There are 4 types of dengue virus that are known to cause dengue fever. The diagnosis of dengue virus infection, in addition to clinical symptoms, needs to be supported by the results of blood tests in the laboratory. A typical picture of DHF laboratory results is an increase in hematocrit accompanied by a decrease in platelets. In patients with dengue fever, hemoconcentration will experience plasma tearing (loss of plasma protein) which will affect the value of the Erythrocyte Sedimentation Rate (LED). Plasma proteins that playa role in influencing the value of the Sedimentation Rate (LED) are fibrinogen and globulins. An erythrocyte sedimentation (LED) examination measures the degree of erythrocyte deposition in a blood sample over a period of time. LEDs are sensitive but not specific tests. Method : Observational analytics, 30 samples with criteria for hemorrhagic fever and nonhemoconcentration patients were examined at the Clinical Pathology Laboratory of Hajj Hospital Surabaya in March-April 2019. The study used an independent t test with SPSS 16.0 program to determine whether there were differences in LED values in patients with fever bleeding with hemoconcentration and not hemoconsetration. Results: The results of the Independent t test showed that there were significant differences between the results of the erythrocyte sedimentation rate in patients with dengue fever with hemoconcentration and not hemoconsetration with Sig. (2-failed) of 0.00 (p <0.005). Conclusion : There were significant differences in sedimentation rate results with the Westergreen blood method in patients with dengue fever who experienced hemoconcentration and who did not experience hemoconcentration. 1. Bakta, I Made. 2006. Hematologi Klinik Ringkas. Jakarta: ECG. 2. Burns C. 2004. Routine hematology procedurs. In McKenzie S. B., editor: Clinical Laboratory Hematology. New Jersey: Pearson Education 3. Eko Sujianto, Agus.2009.Aplikasi Statistic dengan SPSS 16.0. Jakarta: Prestasi Pustaka Publisher. 4. Estridge Bh, Reynolds AP, Walters NJ. 2000. Basic Medical Laboratory Techniques. Albany, New York: Thompson Learning 5. Gandasoebrata, R.,Jr. 1985. Penuntun Laboratorium Klinik. (3 ed). Jakarta: Dian Rakyat. 6. Hadinegoro, Rezeki S, Soegianto S, Soeroso T, Waryadi S. 2001. Tata Laksana Demam Berdarah Dengue di Indonesia. Jakarta: Ditjen PPM&PL Depkes&Kesos R.I. 7. Herdiman T. Pohan. 2004. Man/aat Klinik Pemeriksaan Laju Endap Darah. Dalam: Djoko Widodo, Herdiman T. Pohan (penunting), Bunga Rampai Penyakit Infeksi. Jakarta: Pusat Informasi dan Penerbitan Departemen Ilmu Penyakit Dalam Fakultas Kedokteran Universitas Indonesia. 8. Irwadi D, Arif M, Hardjoeno. 2007. Gambaran Serologi IgM-IgG Cepat dan Hematologi Rutin Penderita DBD. Indonesian: Journal of Clinical Pathology and Medical Laboratory. 9. Jou JM, Lewis SM, Briggs C, Lee SH, De La Salle B, McFadden S. 2011. Review O/The Measurement O/The Erytrhocyte Sedimentation Rate. ICSH 10. Kowalak JP. 2010. Buku Pegangan Uji Diagnostik (Edisi 3). Mustaqin H, Ramadhani D, editors. Jakarta: EGC. 11. Kresno. 1998. Pedoman Pemeriksaan Laboratorium dan Diagnostik. Ed 6. Jakarta: ECG 12. Kristina, lsmaniah, Wulandari L. 2004. Kajian Masalah Kesehatan : Demam Berdarah Dengue. In: Balitbangkes, editor.: Tri Djoko Wahono. 13. Lestari K. 2007. Epidemiologi Dan Pencegahan Demam Berdarah Dengue (DBD) Di Indonesia. Indonsia: Farmaka. 14. Purwanto. 2002. Pemeriksaan Laboratorium Pada Penderita Demam Berdarah Dengue. Media Litbang Kesehatan. 15. PUSDIKNAKES DEPKES RI. 1989. Hematoiogi, Jilid I. Jakarta: PUSDIKNAKES DEPKES RI. 16. Souza LJ, Reis AFF, Almeida FeR, Souza LA, Abukater M, Gomes MAE, et al. 2008. Alterations in the erythrocyte sedimentation rate in dengue patients: analysis of 1,398 cases. Braz J Infect Dis. 17. Stanislaus. 2006. Pedoman Analisis Data dengan SPSS 16.0. Yogyakarta: Penerbit Graha Ilmu. 18. WHO. 2003. Pencegahan dan Penanggulangan Penyakit Demam Dengue dan Demam Berdarah Dengue. Jakarta: WHO & Departemen Kesehatan RI.

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