Yunias Setiawati and H.J. Mukono and Joni Wahyuhadi and Endang Warsiki (2020) Is there an Effect of Serotonin on Attention Deficit Hyperactivity Disorder. Indian Journal of Public Health Research & Development an International Journal, 11 (1). pp. 1745-1749. ISSN 09760245

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Abstract

Background: Attention deficit hyperactivity disorder (ADHD) is a neurobiological disorder with a prevalence of 5%-10% in the world that negatively impacts school behavior and achievement. There have been many studies reveals that attention disorders are caused by the decreased levels of dopamine and norepinephrine neurotransmitter. However, particular concern nowadays are the emotional and behavioral problems. The emotional and behavioral problem is suspected to be caused by the decrease in serotonin level. The aim of this study was to determine the difference in serotonin level between ADHD and non-ADHD children. Method: This study was an observational case-control study design using random sampling method. Subject of this study was children in Bina Karya Elementary School Surabaya. ADHD severity was assessed using Conners Abreviated Rating Scale. Examination of serotonin levels in blood was done by ELISA method. Informed consent was signed by parents before the study. Data was analyzed using independent T-test. Results: 44 (23 ADHD and 21 non-ADHD) children from grade 1 to 6 was included in the study. Based on the gender, 13 children were girls and 31 children were boys. Serotonin level in ADHD children was significantly higher than non-ADHD children (2.148 ± 0.94 vs 2.006 ± 0.115 ?mol/L; p = 0.0001). Conclusion: Serotonin level in ADHD children was significantly higher than non-ADHD children.

Item Type:	Article
Uncontrolled Keywords:	Serotonin, ADHD, Abbreviated Conners Teacher Rating Scale
Subjects:	R Medicine > R Medicine (General) R Medicine > RZ Other systems of medicine
Divisions:	01. Fakultas Kedokteran > Ilmu Kedokteran Jiwa
Creators:	Creators NIM Yunias Setiawati NIDN8837800016 H.J. Mukono UNSPECIFIED Joni Wahyuhadi NIDN8885900016 Endang Warsiki NIDN8829940017
Depositing User:	arys fk
Date Deposited:	09 May 2021 04:29
Last Modified:	09 May 2021 04:29
URI:	http://repository.unair.ac.id/id/eprint/106894
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