Fecal Calprotectin Associated with Spondyloarthritis Disease Activity Repository

Fecal Calprotectin Associated with Spondyloarthritis Disease Activity

Astu NIndya Jati and Ummi Maimunah and Yuliasih and Iswan Abbas Nusi (2020) Fecal Calprotectin Associated with Spondyloarthritis Disease Activity. International Journal of Pharmaceutical Research, 12 (3). pp. 1414-1417. ISSN 0975-2366

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Official URL: http://www.ijpronline.com/ViewArticleDetail.aspx?I...

Abstract

Background: Fecal calprotectin (FC) is one of fecal biomarkers that has validation to distinguish the organic and functional bowel disease but the relationship with disease activity in Spondyloarthritis (SpA) is still questionable. We determined the correlation of FC to the degree of disease activity on SpA. Material and Method: This cross sectional analytic study involved thirty-two subjects diagnosed with SpA. FC levels were analyzed using ELISA method. The Spondylartritis disease activities were assessed by ASDAS-CRP scores. Results: The median age was 52.5 (23.0-71.0) years with the average ASDAS-CRP score of 2.53 ± 0.61. The median level of FC increased by 58.15 (5.20-269.20) µg/g and was found to be positive (=50 µg/g) in 56.3% subjects. FC levels was significantly correlated with the degree of SpA activity according to ASDAS-CRP scores (r = 0.563; P = 0.001) Conclusion: Fecal Calprotectin associated with the degree of activity in the SpA measured by ASDAS-CRP scores.

Item Type:

Article

Uncontrolled Keywords:

Spondyloarthritis, Fecal Calprotectin, Disease activity, ASDAS-CRP

Subjects:

R Medicine > R Medicine (General)
R Medicine > RC Internal medicine

Divisions:

01. Fakultas Kedokteran > Ilmu Penyakit Dalam

Creators: