Gastrointestinal Manifestations in COVID-19 Infection Repository

Gastrointestinal Manifestations in COVID-19 Infection

Titong Sugihartono and Nur Arafah and Yoshio Yamaoka and Muhammad Miftahussurur (2020) Gastrointestinal Manifestations in COVID-19 Infection. The New Armenian Medical Journal, 14 (4). pp. 70-81. ISSN 18290825

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Official URL: https://ysmu.am/en/journal/vol_14_no_4_2020/

Abstract

Coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 originating from Wuhan, China, has caused an outbreak throughout the world and caused death. The severe acute respiratory syndrome coronavirus 2 enters the body via the angiotensin-converting enzyme 2 receptor, followed by priming by transmembrane serine protease 2 and provides an overview of the respiratory system’s main clinical manifestations, such as shortness of breath,cough, and fever. The gastrointestinal tract also expresses angiotensin-converting enzyme 2 receptors so that it manifests in the gastrointestinal tract, namely decreased appetite, diarrhea, vomiting, and abdominal pain. Complaints in the gastrointestinal tract can appear first or together with complaints in the respiratory tract. Patients with gastrointestinal symptoms have a more severe disease degree than patients without gastrointestinal symptoms, and the majority have a high fever. When infected by Coronavirus disease 2019, there is a prolonged condition of dysbiosis even though the severe acute respiratory syndrome coronavirus 2 virus has been eliminated, and respiratory symptoms are not available. The expression and distribution of angiotensin-converting enzyme in the oral cavity and the discovery of the severe acute respiratory syndrome coronavirus 2 virus in the feces indicate a potential route of infection from Coronavirus disease 2019 through the fecal orally. Pathological findings in the gastrointestinal tract of Coronavirus disease 2019 patients are still limited and still require further research, especially concerning the association with the patient’s previous history of the disease. For the treatment of Coronavirus disease 2019, so far, there has been no special therapy given. All treatments are supportive. In patients who experience diarrhea, evaluating their dehydration status, monitoring electrolyte abnormalities, antispasmodic drugs, and probiotics have been performed.

Item Type:

Article

Uncontrolled Keywords:

severe acute respiratory syndrome coronavirus 2, Coronavirus disease 2019, gastrointestinal, inflammatory bowel disease

Subjects:

R Medicine > R Medicine (General)
R Medicine > RC Internal medicine

Divisions:

01. Fakultas Kedokteran > Ilmu Penyakit Dalam

Creators: