VLADINOL F, NEOLIGNAN COMPOUND FROM THE STEM BARK OF Dryobalanops oblongifolia (DIPTEROCARPACEAE) AND ANTIPLASMODIAL ACTIVITY

Indriani, .- and N.S. Aminah*, .- and N.N. Tri Puspaningsih, .- and Y. Takaya, .- and P. Satrimafitrah, .- (2021) VLADINOL F, NEOLIGNAN COMPOUND FROM THE STEM BARK OF Dryobalanops oblongifolia (DIPTEROCARPACEAE) AND ANTIPLASMODIAL ACTIVITY. Rasayan JOURNAL OF CHEMISTRY, 14 (1). pp. 161-165. ISSN 0974-1496 | e-ISSN: 0976-0083

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Abstract

Drybalanops oblongifolia known as kayu kapur is a plant member of Dipterocarpaceae family. A neolignan, vladinol F, was successfully isolated from the dissolved fraction in acetone-ether of Dryobalanops oblongifolia stem bark. The chemical structure's determination was done based on an analysis of UV-Vis, NMR, and MS spectra and a comparison with the reference. In vitro test of this compound against Plasmodium falciparum 3D7 showed that IC50 value was 3.51 μg/mL.

Item Type: Article
Uncontrolled Keywords: Drybalanops oblongifolia, Neolignan, Vladinol F, Antiplasmodial Activity, Plasmodium falciparum
Subjects: Q Science
Q Science > QD Chemistry
Divisions: 08. Fakultas Sains dan Teknologi > Kimia
Creators:
CreatorsNIM
Indriani, .-UNSPECIFIED
N.S. Aminah*, .-0014056707
N.N. Tri Puspaningsih, .-UNSPECIFIED
Y. Takaya, .-UNSPECIFIED
P. Satrimafitrah, .-UNSPECIFIED
Depositing User: Mr Vega Andi Budiman
Date Deposited: 01 Sep 2021 04:43
Last Modified: 29 Sep 2021 09:22
URI: http://repository.unair.ac.id/id/eprint/109930
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