Achmad Ridwan (2021) Analisis Efektivitas Biaya Penggunaan Fentanil Dibandingkan Oksikodon Pada Pasien Nyeri Pasca Bedah (Penelitian Di Ruang Pulih Sadar (Rr) Bedah Central Rumkital Dr. Ramelan Surabaya). Thesis thesis, Universitas Airlangga.

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Abstract

Background - Fentanyl is the drug often used to control post operative pain, there has been a tendency to switch to oxycodone. Oxycodone has been included in the national formulary (FORNAS) since 2018. In addition, many studies have shown the analgesic effect of oxycodone is better than fentanyl for postoperative pain management. Objective - To analyze the cost-effectiveness of fentanil and oxycodone in postoperative pain patients Methods - A RCT single blind, two group study of 20 patients post operative divided into 2 groups. The first group (n = 10 patients) treated with fentanil and the other group (n = 10 patients) treated with oxycodone. Observations carried out for twelve hours. The efficacy of therapy was measured by NRS pain scale. Results and Conclusion - The NRS pain scale after 12 hours showed no difference both two group, so it could be said that both fentanyl and oxycodone had the same effectiveness in reducing the NRS pain scale. In terms of cost fentanyl and oxycodone, the cost of oxycodone is lower (Rp. 2.208.704) compared in the fentanyl group (Rp. 2.332.000). The ACER value in the two groups showed no significant difference. The oxycodone group is more cost-effectiveness than the fentanyl group with equal effectivity in post operative pain.

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