Melanny Ika Sulistyowati, - and Kholis Amalia Nofianti, - and Suzana, - and Tutuk Budiati, - (2013) In vitro antimalarial activity of chalcone and its derivatives. International Journal of Pharmacy and Pharmaceutical Sciences, 6 (1). pp. 669-671. ISSN 0975-1491

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Abstract

Object: to evaluate in vitro antimalarial activity of chalcone and its derivatives. Method: The Chalcones were tested its anti plasmodial activity against Plasmodium falciparum (3D7 strain) by using candle jar method, introduced by Trager and Jensen (1976). Result and Discussion: The tested compounds gave IC50 (half maximal inhibitory concentration) ranged between 0.242 and > 100 µg/ml. Conclusion: All compounds have lower antimalarial activity than commercially standard antimalarial drug, Chloroquine diphosphate.

Item Type:	Article
Uncontrolled Keywords:	Chalcones, In vitro, Antimalarial activity, Plasmodium falciparum.
Subjects:	R Medicine R Medicine > RS Pharmacy and materia medica R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica R Medicine > RS Pharmacy and materia medica > RS200-201 Pharmaceutical dosage forms
Creators:	Creators NIM Melanny Ika Sulistyowati, - NIDN0005058201 Kholis Amalia Nofianti, - NIDN0025118601 Suzana, - NIDN0027096504 Tutuk Budiati, - NIDN0026014804
Depositing User:	Mr M. Fuad Sofyan
Date Deposited:	21 Sep 2021 04:18
Last Modified:	22 Dec 2021 00:39
URI:	http://repository.unair.ac.id/id/eprint/110133
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