Pengaruh Ekstrak Umbi Porang (Amorphophallus Oncophyllus) Terhadap Kadar Malondialdehid Pada Tikus Putih (Rattus Norvegicus) Yang Diinduksi Indometasin

Nandhardi Adiyasa, - (2021) Pengaruh Ekstrak Umbi Porang (Amorphophallus Oncophyllus) Terhadap Kadar Malondialdehid Pada Tikus Putih (Rattus Norvegicus) Yang Diinduksi Indometasin. Skripsi thesis, UNIVERSITAS AIRLANGGA.

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Abstract

This study aimed to discover the effect of porang tuber (Amorphallus onchopyllus) extract on the level of malondialdehyde (MDA) induced by indomethacin in rat (Rattus norvegicus). Twenty male Wistar Rats (175-225 g) were randomly divided into five groups. C(-) was negative control which was given drug solvent, C(+) was positive control given a extract solvent and indomethacin administration on days 4 to 14, T(1), T(2), and T(3) were groups that were treated with porang tuber extract in dose of 50mg/kg BW, 100mg/kg BW, 200mg/kg BW and indomethacin administration on days 4 to14. Dose of Indomethacin are 5 mg/kg BW and were given one hours after extract administration. The treatment was conducted for 7 days of adaptation and 14 days of total treatments. Blood was taken in manner of intracardiac, serum processing, and malondialdehyde level of identification on day 15. The result showed that there is no significant difference (p>0,05) in C(+) and T(1) groups, among porang tuber treatment groups, as well as C(-) and T(3) groups. It can be concluded that porang tuber was effectively work on lower level of malondialdehyde in dose of 200mg/kg BW.

Item Type: Thesis (Skripsi)
Additional Information: KKC KK KH 135/21 Adi p
Uncontrolled Keywords: Indomethacin, Malondialdehyde, Porang tuber extract
Subjects: S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine
S Agriculture > SF Animal culture > SF84-84.64 Economic zoology
Divisions: 06. Fakultas Kedokteran Hewan > Ilmu Kedokteran Hewan Dasar
Creators:
CreatorsNIM
Nandhardi Adiyasa, -NIM061711133150
Contributors:
ContributionNameNIDN / NIDK
Thesis advisorRochmah Kurnijasanti, -NIDN0019077004
Thesis advisorThomas V Widiyatno, -NIDN0017105809
Depositing User: Unnamed user with email indah.fatma@staf.unair.ac.id
Date Deposited: 14 Oct 2021 20:32
Last Modified: 14 Oct 2021 20:32
URI: http://repository.unair.ac.id/id/eprint/111280
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