Charolyn Menaisa Sembiring, '- (2021) Studi Penggunaan Obat Hipertensi Pulmonal Pada Pasien Rawat Jalan Rumah Sakit Umum dr. Soetomo. Skripsi thesis, Universitas Airlangga.

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Abstract

Pulmonary hypertension (PH) is a life threatening disease caused by increased blood pressure in the arteries lungs especially at the right side of the heart. PH can cause many symptoms such as shortness of breath, dizziness, and can reduce heart function that leads to heart failure. One type of pulmonary hypertension is arterial hypertension (PAH) which known as an idiopathic disease. Management of PAH patients includes pharmacological therapy (supportive therapy and specific therapy) and invasive therapy. This study aims to observe the drug utilization and drug-related problems in outpatient pulmonary hypertension at SMF Cardiology and Vascular Medicine Dr. Soetomo Surabaya from March 2021 to April 2021. The results of 35 patients showed that the drug utilization that was often used in PAH patients included specific therapy, such as sildenafil at 97.14% and beraprost at 88.6%, and supportive therapy include bisoprolol at 62.9% and furosemide at 51.4%. Drug-related problems that found in this study were actual side effects, potential drug interactions, and some inappropriate doses compared to the guidelines. The conclusion of this study showed the profile of specific and supportive drug therapy was mostly appropriate but there were still PAH patients who had severe PASP and experience side effects

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