Sesbagrandiflorain F, a New 2-Arylbenzofuran from the Stem Bark of Sesbania grandiflora L.

Mulyadi Tanjung*, .- and Muhammad Fajar Aldin, .- and Tjitjik Srie Tjahjandarie, .- and Devina Oktari Rahayu, .- and Alfiah Nur Irza Gunawan, .- and Ratih Dewi Saputri, .- (2021) Sesbagrandiflorain F, a New 2-Arylbenzofuran from the Stem Bark of Sesbania grandiflora L. Natural Product Sciences, 27 (3). pp. 172-175. ISSN 12263907

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Official URL: https://www.koreascience.or.kr/article/JAKO2021286...

Abstract

Sesbagrandiflorain F (1), a novel 2-arylbenzofuran, and two more 2-arylbenzofurans (2-3), were isolated from the stem bark of Sesbania grandiflora L. Based on information HRESIMS data, 1D, and 2D NMR spectra, the structure of 1 was fully assigned. Compounds 1-3 were tested for cytotoxicity in MCF-7 and HeLa cells. Compounds 1 and 3 showed moderate activity against MCF-7 cells with an IC50 value of 2.68 and 4.08 ㎍/mL, respectively. Conversely, all of the isolates were inactive towards HeLa cells.

Item Type: Article
Uncontrolled Keywords: Sesbagrandiflorain F; 2-Arylbenzofuran; Sesbania grandiflora; Cytotoxic
Subjects: Q Science
Q Science > Q Science (General)
Q Science > QD Chemistry
Divisions: 08. Fakultas Sains dan Teknologi > Kimia
Creators:
CreatorsNIM
Mulyadi Tanjung*, .-UNSPECIFIED
Muhammad Fajar Aldin, .-UNSPECIFIED
Tjitjik Srie Tjahjandarie, .-UNSPECIFIED
Devina Oktari Rahayu, .-UNSPECIFIED
Alfiah Nur Irza Gunawan, .-UNSPECIFIED
Ratih Dewi Saputri, .-UNSPECIFIED
Depositing User: Mr Vega Andi Budiman
Date Deposited: 01 Dec 2021 07:38
Last Modified: 21 Dec 2021 04:03
URI: http://repository.unair.ac.id/id/eprint/112667
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