Potentials of Nggorang Leaf Standard Extract (Salvia Ccidentalis) Study: Ethnopharmacology, Standardization, Antioxoxide, Sitotoxicity and Working Mechanisms

Sicily Teresia Rosmala Dewi, - and Chatarina UW Ahjuni, - and Sukardiaman, - and Eduardus Bimo Aksono Herupradoto, - and Sesilia Rante Pakadang, - and Santi Sinala, - and Jumain, - (2019) Potentials of Nggorang Leaf Standard Extract (Salvia Ccidentalis) Study: Ethnopharmacology, Standardization, Antioxoxide, Sitotoxicity and Working Mechanisms. Indian Journal of Public Health Research & Development, 10 (11). pp. 2340-2344. ISSN 0976-0245 Online ISSN : 0976-5506

[img] Text (Journal)
Artikel_11_Eduardus_Bimo.pdf

Download (2MB)
[img] Text (Kesesuaian Bidang Ilmu)
Kesesuaian_11_Eduardus_Bimo.pdf

Download (325kB)
[img] Text (Peer Review)
Peer_Review_11_Eduardus_Bimo_Aksono.PDF

Download (1MB)
[img] Text (Turn It In)
Similarity_11_Eduardus_Bimo_Aksono.PDF

Download (1MB)
Official URL: https://ijphrd.com/issues.html

Abstract

The use of medicinal plants is used as the main therapy as well as additional therapy to enhance one’s immunity or maintain health and fitness. Nggorang Leaf Extract (EDG) polyphenol and flavonoid compounds and essential oils. Flavonoids are powerful antioxidants that work as a cancer prevention and also have antimicrobial effects. This study aims to prove the potential of EDG as an antioxidant and antiproliferation of Hela cancer cells. This research includes Quasy experiment research The conclusion of this study shows that Nggorang Leaf Extract (EDG) has potential as an antioxidant against DPPH radicals at IC50 = 34,407 ppm; Nggorang Leaf Extract (EDG) has potential as an antiproliferation of T47D IC50 cancer cells = 201 ppm; Nggorang Leaf Extract (EDG) has potential as an antiproliferation of Hela IC50 cancer cells = 187 ppm; Nggorang Leaf Extract (EDG) has the potential to reduce ROS activity in T47D cancer cells by 54.34% at a concentration of 50 ppm; Nggorang Leaf Extract (EDG) has the potential to reduce ROS activity in Hela cancer cells by 58.33% at a concentration of 50 ppm; Nggorang Leaf Extract (EDG) has the potential to increase P53 gene expression in T47D cancer cells by 94.13% at a concentration of 50 ppm; Nggorang Leaf Extract (EDG) has the potential to increase P53 gene expression in Hela cancer cells by 92.05% at a concentration of 50 ppm. The novelty of this study is that Nggorang leaves (Salvia occidentalis) can be used as a preventative for breast cancer and cervical cancer. Keywords : Salvia Occidentalis, Ethnopharmacology

Item Type: Article
Uncontrolled Keywords: Salvia Occidentalis, Ethnopharmacology
Subjects: S Agriculture > SF Animal culture > SF600-1100 Veterinary medicine > SF910 Other diseases and conditions
Divisions: 06. Fakultas Kedokteran Hewan > Klinik Veteriner
Creators:
CreatorsNIM
Sicily Teresia Rosmala Dewi, --
Chatarina UW Ahjuni, --
Sukardiaman, --
Eduardus Bimo Aksono Herupradoto, -NIDN0068611236
Sesilia Rante Pakadang, --
Santi Sinala, --
Jumain, --
Depositing User: Nn Erna Dwi Indriyani
Date Deposited: 07 Jan 2022 00:39
Last Modified: 06 May 2023 07:34
URI: http://repository.unair.ac.id/id/eprint/113059
Sosial Share:

Actions (login required)

View Item View Item