Ma'rifat Istiqa Mukty, - and Bambang Wirjatmadi, - and Bambang Purwanto, - (2018) Effect Of Green Tea (Camelia Sinensis) On Activity Of Superoxide Dismutase (SOD). International Journal of Public Health and Clinical Sciences, 5 (6). pp. 95-103. ISSN 2289-7577

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Abstract

Background: Oxidative stress can be triggered by exposure to psychological stress. Oxidative stress can be reduced by the consumption of exogenous antioxidants, green tea is considered able to reduce oxidative stress. The purpose of this study to examine the effect of green tea steeping on superoxide dismutase (SOD) activity in male rats strain Wistar which exposed to psychological stress. Materials and Methods: This study used Randomized Post Test Only Group Design. There were five groups of rats, i.e. normal control group, stress control group, first, second, and third treatment groups. Psychological stress were given to rats for 1 x 24 hours, and then the green tea steeping were given into the three treatment group with a single dose of 3.6 ml, and were examined the SOD activity in the 1st hour, 6th hour and 24th hour. Statistical analysis used Multivariate Analysis of Variance (Manova) test. Result: The result of this study, based on statistical analysis showed that there were differences SOD activity increased in 1st hour, to increase again in the 6th hour and maximum increased in 24th hour after given of green tea steeping. Conclusion: A single dose of green tea steeping in animals which undergo oxidative stress has proven to neutralize oxidative stress in all 1st hour after given of green tea steeping and its antioxidant activity remains for up to 24 hour.

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