Aryati, - and Puspa Wardhani, - (2010) Profil Virus Dengue di Surabaya Tahun 2008-2009 (Dengue Virus Profile in Surabaya From 2008-2009). Indonesian Journal of Clinical Pathology and Medical Laboratory, 17 (1). pp. 21-24. ISSN 0854-4263

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Abstract

Four serotypes of dengue viruses (DENV) 1–4 are mosquito-borne human pathogens that cause widespread epidemics with considerable morbidity and mortality. The aim of this study was to evaluate the dengue serotypes profile, which were circulating in Surabaya. This research has been carried out consisting of 360 samples from patients with dengue virus infections, according the World Health Organization (WHO) criteria. These sera were collected from patients Dr. Soetomo Hospital and private laboratory in Surabaya from 2008–2009. From 360 samples, 68 samples (18.9%) were undifferentiated fever, 53 samples (14.7%) were dengue fever, 239 samples (66.4%) were dengue hemorrhagic fever. From 58 Reverse Transcriptase Polymerase Chain Reaction (RT-PCR) samples, 25 samples (43%) were positive, consisting of 52% DEN-2, 20% DEN-1, 16% DEN-3 and 12% DEN-4. These results showed that four serotypes are circulating in Indonesia, dominated by DEN-2, followed by DEN-1, DEN-3 and DEN-4.

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