Amrina Rosyada, - and Sulistiawati, - and Dominicus Husada, - and Jusak Nugraha, - (2017) Comparison Of Blood Group Based On Bleeding Manifestation In Pediatric- Dengue Cases. In: Proceeding of the ICHS 2017 Proceeding of the 2nd International Conference on Health Sciences. Badan Penerbit dan Publikasi Universitas Gadjah Mada, Yogyakarta, pp. 1-5. ISBN https://doi.org/10.29037/digitalpress.31222

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Abstract

Bleeding manifestation in dengue cases presents due to the impairment of blood homeostasis. Previous studies mentioned that blood group O have higher bleeding risk because of lower blood coagulation von Willebran Factor (vWF) and factor VIII (FVIII) compared to non-O blood groups. This study was aiming to identify the comparison of blood group based on bleeding manifestation in pediatric dengue cases. The method used was a cross-sectional study with consecutive sampling in Pediatric Inpatient Ward Dr. Soetomo General Hospital, Surabaya, Indonesia, during March–September 2016. The study involved 86 dengue pediatric patients with 52 patients that fulfilled the inclusive criteria. The blood group, diagnosis, and the presence of bleeding manifestation data were collected from medical records and analyzed using chi-square test with p-value <0.05 and confidence interval 95 %. Blood group was divided based on ABO blood group system and based on blood group O and non-O. The results showed that there was no significant difference between ABO blood group based on the presence of bleeding manifestation (p = 0.579), and there was no significant difference between blood group O and non-O based on the presence of bleeding manifestation (p = 0.600). In this study, there was no significant difference between blood group based on bleeding manifestation in pediatric dengue cases. The previous bleeding risk theory based on blood coagulation factor was not proven based on this research.

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