Adil Astulla, - and Kazumasa Zaima, - and Yosuke Matsuno, - and Yusuke Hirasawa, - and Wiwied Ekasari, - and Aty Widyawaruyanti, - and Noor Cholies Zaini, - and Hiroshi Morita, - (2008) Alkaloids from the seeds of Peganum harmala showing antiplasmodial and vasorelaxant activities. Journal of Natural Medicines, 62 (4). pp. 470-472. ISSN 1340-3443
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Abstract
Bioassay-guided purification from the seeds of Peganum harmala led to the isolation of harmine (1), harmaline (2), vasicinone (3), and deoxyvasicinone (4). Harmine (1) and harmaline (2) showed a moderate in vitro antiplasmodial activity against Plasmodium falciparum. Quinazoline alkaloid, vasicinone (3), showed a vasorelaxant activity against phenylephrine-induced contraction of isolated rat aorta.
| Item Type: | Article | ||||||||||||||||||
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| Subjects: | R Medicine R Medicine > RS Pharmacy and materia medica R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica R Medicine > RS Pharmacy and materia medica > RS200-201 Pharmaceutical dosage forms |
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| Divisions: | 05. Fakultas Farmasi > Farmakognosi Fitokimia | ||||||||||||||||||
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| Depositing User: | Mr M. Fuad Sofyan | ||||||||||||||||||
| Date Deposited: | 27 May 2022 09:08 | ||||||||||||||||||
| Last Modified: | 02 Aug 2022 08:17 | ||||||||||||||||||
| URI: | http://repository.unair.ac.id/id/eprint/116530 | ||||||||||||||||||
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