Alstiphyllanines A-D, Indole Alkaloids from Alstonia macrophylla

Yusuke Hirasawa, - and Hiroko Arai, - and Kazumasa Zaima, - and Rice Disi Oktarina, - and Abdul Rahman, - and Wiwied Ekasari, - and Aty Widyawaruyanti, - and Gunawan Indrayanto, - and Noor Cholies Zaini, - and Hiroshi Morita, - (2009) Alstiphyllanines A-D, Indole Alkaloids from Alstonia macrophylla. Journal of Natural Products, 72 (2). pp. 304-307. ISSN ISSN: 0163-3864

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Official URL: https://pubs.acs.org/doi/abs/10.1021/np8007107

Abstract

Four new alkaloids, alstiphyllanines A−D (1−4), were isolated from Alstonia macrophylla, and their structures were determined by MS and 2D NMR analyses. Alkaloids 1−4 showed moderate antiplasmodial activity against Plasmodium falciparum and vasorelaxant activity against phenylephrine-induced contraction of isolated rat aorta.

Item Type: Article
Subjects: R Medicine
R Medicine > RS Pharmacy and materia medica
R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
R Medicine > RS Pharmacy and materia medica > RS200-201 Pharmaceutical dosage forms
Divisions: 05. Fakultas Farmasi > Farmakognosi Fitokimia
Creators:
CreatorsNIM
Yusuke Hirasawa, --
Hiroko Arai, --
Kazumasa Zaima, --
Rice Disi Oktarina, -NIDN0005087905
Abdul Rahman, --
Wiwied Ekasari, -NIDN0022016902
Aty Widyawaruyanti, -NIDN0026046210
Gunawan Indrayanto, --
Noor Cholies Zaini, --
Hiroshi Morita, --
Depositing User: Mr M. Fuad Sofyan
Date Deposited: 30 May 2022 00:28
Last Modified: 02 Aug 2022 08:19
URI: http://repository.unair.ac.id/id/eprint/116542
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