Adiastuti Endah Parmadiati, - and Diah Savitri Ernawati, - and Bagus Soebadi, - and Alexander Patera Nugraha, - and Erwin Asta Triyono, - and Remita Adya Prasetyo, - and Sulistyowati Budi, - (2017) Correlation Oral Hairy Leukoplakia and CD4+ Counts in HIV/AIDS Patient at Dr. Soetomo Hospital Surabaya, Indonesia 2014. Journal of International Dental and Medical Research, 10 (1). pp. 162-165. ISSN 1309-100X

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Abstract

Indonesia is a one of the countries in South East Asia with a high prevalence of HIV/AIDS cases. Oral Hairy Leukoplakia (OHL) is the one of the oral manifestations that often found in HIV/AIDS patient decreased CD4+ counts. OHL play an important role and it can be used as a clinical biomarker to determine the stage, progression, predict the onset of opportunistic diseases and a strong indicator of immunodeficiency condition. The aim of this study to investigate correlation OHL and CD4+ counts in HIV/AIDS patients at UPIPI RSUD DR. Soetomo Surabaya 2014. This study was an analytic observational study with cross-sectional and total sampling method was conductet at UPIPI RSUD Dr. Soetomo. The samples consisted of 88 HIV/AIDS patients from July-August 2014. Diagnosed of OHL based on clinical appearance, the oral cavity of research subjects examined by oral medicine specialist. CD4+ counts obtained from patient’s medical record. 88 HIV/AIDS patients were examined; there were 15 patients with OHL (17,05%). OHL was found to be significantly correlated to decreased of CD4+ counts <200 cells/mm3 (p < 0.05). Decreased of CD4+ counts affect the occurrence of OHL. OHL may be used as an alternative to CD4 count to diagnose the immunodeficiency HIV/AIDS patients. Clinical article (J Int Dent Med Res 2017; 10: (1), pp. 162-165) Keywords: Oral Hairy Leukoplakia, HIV/AIDS, CD4+, Clinical Biomarker, Oral Manifestation. Received date: 14 March 2017 Accept date: 29 March 2017

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