Alasmontamine A, A First Tetrakis Monoterpene Indole Alkaloid from Tabernaemontana elegans

Yusuke Hirasawa, - and Saori Miyama, - and Takahiro Hosoya, - and Koichiro Koyama, - and Abdul Rahman, - and Idha Kusumawati, - and Noor Cholies Zaini, - and Hiroshi Morita, - (2009) Alasmontamine A, A First Tetrakis Monoterpene Indole Alkaloid from Tabernaemontana elegans. ORGANIC LETTERS, 11 (24). pp. 8718-8721. ISSN 1523-7052

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Official URL: https://pubs.acs.org/doi/10.1021/ol902420s

Abstract

A novel tetrakis monoterpene indole alkaloid, alasmontamine A (1) consisting of bis-vobtusine-type skeletons, was isolated from the leaves of Tabernaemontana elegans. The structure including the relative stereochemistry was elucidated on the basis of spectroscopic data. Alasmontamine A (1) exhibited moderate cell growth inhibitory activity against HL-60 cells.

Item Type: Article
Subjects: R Medicine
R Medicine > RS Pharmacy and materia medica
R Medicine > RS Pharmacy and materia medica > RS1-441 Pharmacy and materia medica
R Medicine > RS Pharmacy and materia medica > RS200-201 Pharmaceutical dosage forms
Divisions: 05. Fakultas Farmasi > Farmakognosi Fitokimia
Creators:
CreatorsNIM
Yusuke Hirasawa, --
Saori Miyama, --
Takahiro Hosoya, --
Koichiro Koyama, --
Abdul Rahman, --
Idha Kusumawati, -NIDN0004087003
Noor Cholies Zaini, --
Hiroshi Morita, --
Depositing User: Mr M. Fuad Sofyan
Date Deposited: 08 Jul 2022 03:38
Last Modified: 26 Mar 2023 07:48
URI: http://repository.unair.ac.id/id/eprint/116997
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